Validation of the γH2AX biomarker for genotoxicity assessment: a review

B Kopp, L Khoury, M Audebert - Archives of toxicology, 2019 - Springer
The H2AX histone protein is rapidly phosphorylated at the serine-139 position (γH2AX) in
response to a broad range of DNA lesions. γH2AX induction is one of the earliest events in …

A systematic review of the genotoxicity and antigenotoxicity of biologically synthesized metallic nanomaterials: are green nanoparticles safe enough for clinical …

H Barabadi, M Najafi, H Samadian, A Azarnezhad… - Medicina, 2019 - mdpi.com
Background and objectives: Although studies have elucidated the significant biomedical
potential of biogenic metallic nanoparticles (MNPs), it is very important to explore the …

To decipher the phytochemical agent and mechanism for Urginea indica mediated green synthesis of Ag nanoparticles and investigation of its antibacterial activity …

B Jena, SS Singh, SK Behera, S Mishra… - Environmental …, 2023 - Elsevier
Abstract Globally, Methicillin-Resistant Staphylococcus aureus bacteraemia is one of the
commonest bloodstream infections associated with clinical complications and high mortality …

New in silico models to predict in vitro micronucleus induction as marker of genotoxicity

D Baderna, D Gadaleta, E Lostaglio… - Journal of hazardous …, 2020 - Elsevier
The evaluation of genotoxicity is a fundamental part of the safety assessment of chemicals
due to the relevance of the potential health effects of genotoxicants. Among the testing …

Established antibacterial drugs from plants

AJ Seukep, HG Mbuntcha, EM Zeuko'o… - Advances in Botanical …, 2023 - Elsevier
Plants hold great promise as a source of novel antimicrobial agents due to a wide variety of
chemically and structurally diverse secondary metabolites generally grouped into …

Teratogenic Effect of High Dose of Syzygium guineense (Myrtaceae) Leaves on Wistar Albino Rat Embryos and Fetuses

M Abebe, K Asres, Y Bekuretsion… - Evidence‐Based …, 2021 - Wiley Online Library
Syzygium guineense is an important medicinal plant effective against hypertension,
diabetes mellitus, and cancer but with no evidence of its teratogenicity. This study was …

A Comprehensive Account on Ethnobotany, Phytochemistryand Pharmacological Insights of Genus Celtis

MA Samadd, MJ Hossain, MS Zahan, MM Islam… - Heliyon, 2024 - cell.com
Celtis L. genus has been traditionally used to cure aches, sore throats, fevers, cancer,
sexually transmitted diseases, sexual weakness, diarrhea, stomach problems, amenorrhea …

Genotoxicity and mutagenicity assessment of food contaminant mixtures present in the French diet

B Kopp, J Vignard, G Mirey, V Fessard… - Environmental and …, 2018 - Wiley Online Library
Through diet, people are exposed simultaneously to a variety of contaminants (eg heavy
metals, mycotoxins, pesticides) that could have combined adverse effects on human health …

Modulation of inflammatory pathways, medicinal uses and toxicities of Uvaria species: potential role in the prevention and treatment of inflammation

J Jalil, A Attiq, CC Hui, LJ Yao, NA Zakaria - Inflammopharmacology, 2020 - Springer
The therapeutic efficacy of the contemporary anti-inflammatory drugs are well established;
however, prolonged use of such can often lead to serious and life-threatening side effects …

Teratogenic Evaluation of 80% Ethanol Extract of Embelia schimperi Vatke Fruits on Rat Embryo and Fetuses

Z Animaw, K Asres, S Tadesse, H Basha… - Journal of …, 2022 - Wiley Online Library
Introduction. Embelia schimperi Vatke (family Myrsinaceae) is a commonly consumed
anthelminthic plant in Ethiopia. The plant has significant efficacy in treating intestinal worms …