Heart failure is the leading cause of death worldwide, and current therapies only delay
progression of the disease. Laboratory experiments and recent clinical trials suggest that …

The important role of the vascular endothelium in cardiovascular health is increasingly
recognized. However, mature endothelial cells possess limited regenerative capacity. There …

Colony-forming units–fibroblast (CFU-Fs), analogous to those giving rise to bone marrow
(BM) mesenchymal stem cells (MSCs), are present in many organs, although the …

Myocardial infarction rapidly depletes the endogenous cardiac progenitor cell pool, and the
inefficient recruitment of exogenously administered progenitor cells limits the effectiveness …

Potential applications of tissue engineering in regenerative medicine range from structural
tissues to organs with complex function. This review focuses on the engineering of heart …

Cell therapy is a promising option for treating ischemic diseases and heart failure. Adult
stem and progenitor cells from various sources have experimentally been shown to augment …

considered unusual cells that are created only during embryonic and fetal development so
that their total number in the heart is established at birth and no further growth occurs …

Rationale: High-sensitivity in vivo phenoty** of cardiac function is essential for evaluating
genes of interest and novel therapies in small animal models of cardiovascular disease …

Traditionally associated with female reproduction, oxytocin (OT) was revisited recently and
was revealed to have several new roles in the cardiovascular system. Functional OT …

Cell-based therapy is a promising option for treatment of ischemic diseases. Several cell
types have experimentally been shown to increase the functional recovery of the heart after …