Organophosphorus nerve agents: types, toxicity, and treatments

S Mukherjee, RD Gupta - Journal of toxicology, 2020 - Wiley Online Library
Organophosphorus compounds are extensively used worldwide as pesticides which cause
great hazards to human health. Nerve agents, a subcategory of the organophosphorus …

[HTML][HTML] FDA-approved oximes and their significance in medicinal chemistry

J Dhuguru, E Zviagin, R Skouta - Pharmaceuticals, 2022 - mdpi.com
Despite the scientific advancements, organophosphate (OP) poisoning continues to be a
major threat to humans, accounting for nearly one million poisoning cases every year …

A-series agent A-234: initial in vitro and in vivo characterization

M Hrabinova, J Pejchal, V Hepnarova, L Muckova… - Archives of …, 2024 - Springer
A-series agent A-234 belongs to a new generation of nerve agents. The poisoning of a
former Russian spy Sergei Skripal and his daughter in Salisbury, England, in March 2018 …

A-agents, misleadingly known as “Novichoks”: a narrative review

J Opravil, J Pejchal, V Finger, J Korabecny… - Archives of …, 2023 - Springer
Abstract “Novichok” refers to a new group of nerve agents called the A-series agents. Their
existence came to light in 2018 after incidents in the UK and again in 2020 in Russia. They …

Application of toxicology in silico methods for prediction of acute toxicity (LD50) for Novichoks

M Noga, A Michalska, K Jurowski - Archives of toxicology, 2023 - Springer
Novichoks represent the fourth generation of chemical warfare agents with paralytic and
convulsive effects, produced clandestinely during the Cold War by the Soviet Union. This …

Effective degradation of Novichok nerve agents by the zirconium metal–organic framework MOF-808

MC de Koning, C Vieira Soares… - … Applied Materials & …, 2022 - ACS Publications
Novichoks are a novel class of nerve agents (also referred to as the A-series) that were
employed in several poisonings over the last few years. This calls for the development of …

Recent research on Novichok

HM Bolt, JG Hengstler - Archives of toxicology, 2022 - Springer
The first organophosphate intoxication cases that were published in Archives of Toxicology
were caused by parathion (E605), and a high acute toxicity of this chemical was noted, at a …

The acute toxicity of Novichok's degradation products using quantitative and qualitative toxicology in silico methods

M Noga, A Michalska, K Jurowski - Archives of toxicology, 2024 - Springer
The emergence of Novichok agents, potent organophosphorus nerve agents, has spurred
the demand for advanced analytical methods and toxicity assessments as a result of their …

What do we currently know about Novichoks? The state of the art

M Noga, K Jurowski - Archives of toxicology, 2023 - Springer
Novichok is the name given to the group of nerve agents created stealthily in the later
phases of the Cold War by the Soviet Union. Constitute the fourth generation of chemical …

Novichok toxicology: A review study

F Voiţă-Mekereş, C Delcea, CL Buhaș… - Archives of Pharmacy …, 2023 - archivepp.com
One of the most important types of chemical weapons is nerve agents. In recent years, a
group of the newest, most unknown, and at the same time the most common nerve agents …