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SUMO and the DNA damage response
JS Bhachoo, AJ Garvin - Biochemical Society Transactions, 2024 - portlandpress.com
The preservation of genome integrity requires specialised DNA damage repair (DDR)
signalling pathways to respond to each type of DNA damage. A key feature of DDR is the …
signalling pathways to respond to each type of DNA damage. A key feature of DDR is the …
Recent Advances in Develo** Targeted Protein Degraders
B Cheng, H Li, X Peng, J Chen, C Shao… - European Journal of …, 2024 - Elsevier
Targeted protein degradation (TPD) represents a promising therapeutic approach,
encompassing several innovative strategies, including but not limited to proteolysis targeting …
encompassing several innovative strategies, including but not limited to proteolysis targeting …
RNF4 prevents genomic instability caused by chronic DNA under-replication
MK Oram, RM Baxley, EM Simon, K Lin, YC Chang… - DNA repair, 2024 - Elsevier
Eukaryotic genome stability is maintained by a complex and diverse set of molecular
processes. One class of enzymes that promotes proper DNA repair, replication and cell …
processes. One class of enzymes that promotes proper DNA repair, replication and cell …
[HTML][HTML] The Role and Mechanism of Deubiquitinase USP7 in Tumor-Associated Inflammation
L Wang, Y Zhang, T Yu, H Wu - Biomedicines, 2024 - mdpi.com
Deubiquitinating enzymes are a class of proteases that remove ubiquitin tags from proteins,
thereby controlling protein stability and function. Tumor inflammation arises from interactions …
thereby controlling protein stability and function. Tumor inflammation arises from interactions …