[HTML][HTML] Butyrate's role in human health and the current progress towards its clinical application to treat gastrointestinal disease

K Hodgkinson, F El Abbar, P Dobranowski… - Clinical Nutrition, 2023 - Elsevier
Butyrate is a key energy source for colonocytes and is produced by the gut microbiota
through fermentation of dietary fiber. Butyrate is a histone deacetylase inhibitor and also …

Understanding the role of the gut microbiome in gastrointestinal cancer: A review

D Ağagündüz, E Cocozza, Ö Cemali… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal cancer represents one of the most diagnosed types of cancer. Cancer is a
genetic and multifactorial disease, influenced by the host and environmental factors. It has …

Bacterial biofilm and its role in the pathogenesis of disease

LK Vestby, T Grønseth, R Simm, LL Nesse - Antibiotics, 2020 - mdpi.com
Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease
has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm …

[HTML][HTML] Lactobacillus and intestinal diseases: Mechanisms of action and clinical applications

R Huang, F Wu, Q Zhou, W Wei, J Yue, B **ao… - Microbiological …, 2022 - Elsevier
The gut microbial ecosystem, which is a collection of the host-microbiota interactions and the
inter-species interplay among bacteria-dominated microbiota, has become a research …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Diet, microorganisms and their metabolites, and colon cancer

SJD O'keefe - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
Colorectal cancer is one of the so-called westernized diseases and the second leading
cause of cancer death worldwide. On the basis of global epidemiological and scientific …

Roseburia Spp.: A Marker of Health?

Z Tamanai-Shacoori, I Smida, L Bousarghin… - Future …, 2017 - Taylor & Francis
The genus Roseburia consists of obligate Gram-positive anaerobic bacteria that are slightly
curved, rod-shaped and motile by means of multiple subterminal flagella. It includes five …

Metagenomic analysis of gut microbiota modulatory effects of jujube (Ziziphus jujuba Mill.) polysaccharides in a colorectal cancer mouse model

X Ji, C Hou, Y Gao, Y Xue, Y Yan, X Guo - Food & function, 2020 - pubs.rsc.org
Accumulating evidence has reported that the gut microbiota could play important roles in the
occurrence and progression of colorectal cancer. The nondigestible plant polysaccharides …

Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin

Z He, RZ Gharaibeh, RC Newsome, JL Pope… - Gut, 2019 - gut.bmj.com
Objective Campylobacter jejuni produces a genotoxin, cytolethal distending toxin (CDT),
which has DNAse activity and causes DNA double-strand breaks. Although C. jejuni …