HIV‐associated chronic immune activation
M Paiardini, M Müller‐Trutwin - Immunological reviews, 2013 - Wiley Online Library
Systemic chronic immune activation is considered today as the driving force of CD 4+ T‐cell
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune …
Tolerance of infections
JS Ayres, DS Schneider - Annual review of immunology, 2012 - annualreviews.org
A host has two methods to defend against pathogens: It can clear the pathogens or reduce
their impact on health in other ways. The first, resistance, is well studied. Study of the …
their impact on health in other ways. The first, resistance, is well studied. Study of the …
Prevalence and comparative characteristics of long-term nonprogressors and HIV controller patients in the French Hospital Database on HIV
S Grabar, H Selinger-Leneman, S Abgrall, G Pialoux… - Aids, 2009 - journals.lww.com
Objective: To estimate the prevalence and characteristics of long-term nonprogressor
(LTNP) and HIV controller patients in a very large French cohort of HIV1-infected patients …
(LTNP) and HIV controller patients in a very large French cohort of HIV1-infected patients …
Modelling HIV-1 control and remission
Remarkable advances are being made in develo** interventions for eliciting long-term
remission of HIV-1 infection. The success of these interventions will obviate the need for …
remission of HIV-1 infection. The success of these interventions will obviate the need for …
Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque
High levels of HIV-1 replication during the chronic phase of infection usually correlate with
rapid progression to severe immunodeficiency. However, a minority of highly viremic …
rapid progression to severe immunodeficiency. However, a minority of highly viremic …
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts
The design of an effective AIDS vaccine has eluded the efforts of the scientific community to
the point that alternative approaches to classic vaccine formulations have to be considered …
the point that alternative approaches to classic vaccine formulations have to be considered …
CCR5 as a coreceptor for human immunodeficiency virus and simian immunodeficiency viruses: a prototypic love-hate affair
AJ Jasinska, I Pandrea, C Apetrei - Frontiers in Immunology, 2022 - frontiersin.org
CCR5, a chemokine receptor central for orchestrating lymphocyte/cell migration to the sites
of inflammation and to the immunosurveillance, is involved in the pathogenesis of a wide …
of inflammation and to the immunosurveillance, is involved in the pathogenesis of a wide …
Human immunodeficiency virus (HIV) immunopathogenesis and vaccine development: a review
MP Girard, S Osmanov, OM Assossou, MP Kieny - Vaccine, 2011 - Elsevier
The development of a safe, effective and globally affordable HIV vaccine offers the best
hope for the future control of the HIV-1 pandemic. Since 1987, scores of candidate HIV-1 …
hope for the future control of the HIV-1 pandemic. Since 1987, scores of candidate HIV-1 …
Chronic CD4+ T-Cell Activation and Depletion in Human Immunodeficiency Virus Type 1 Infection: Type I Interferon-Mediated Disruption of T-Cell Dynamics
The mechanism of CD4+ T-cell depletion during chronic human immunodeficiency virus
type 1 (HIV-1) infection remains unknown. Many studies suggest a significant role for chronic …
type 1 (HIV-1) infection remains unknown. Many studies suggest a significant role for chronic …
HIV control: Is getting there the same as staying there?
In this brief review and perspective, we address the question of whether the immune
responses that bring about immune control of acute HIV infection are the same as, or distinct …
responses that bring about immune control of acute HIV infection are the same as, or distinct …