During embryonic development and adulthood, Reelin exerts several important functions in
the brain including the regulation of neuronal migration, dendritic growth and branching …

Over the last 50 years, the reeler mutant mouse has become an important model for studying
normal and abnormal development in the cerebral cortex and other regions of the brain …

Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with
drug‐resistant temporal lobe epilepsy (TLE). Over the past decades, various attempts have …

Multiple sclerosis (MS), a chronic disorder of the central nervous system and common cause
of neurological disability in young adults, is characterized by moderate but complex risk …

Apolipoprotein E (APOE) is a cholesterol transport protein and an isoform-specific major risk
factor for neurodegenerative diseases. The lipoprotein receptors that bind APOE have …

In many patients who suffer from epilepsies, recurrent epileptic seizures do not start at birth
but develop later in life. This holds particularly true for epilepsies with a focal seizure origin …

Clinical and experimental evidence indicates that inflammatory processes contribute to the
pathophysiology of epilepsy, but underlying mechanisms remain mostly unknown. Using …

Abstract Between 1997 and 2002, 48 data sets from the hippocampus were produced on
samples from the Stanley Neuropathology Consortium. From these data sets, 224 total …

INTRODUCTION The function of the brain relies on communication among the complex
network of cells that constitute this organ. Vascularization of the central nervous system …

Neurogenesis in the hippocampal dentate gyrus persists throughout life and is increased by
seizures. The dentate granule cell (DGC) layer is often abnormal in human and …