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Zebrafish: a model system for the study of human disease
K Dooley, LI Zon - Current opinion in genetics & development, 2000 - Elsevier
The zebrafish (Danio rerio) is a powerful model organism for the study of vertebrate biology,
being well suited to both developmental and genetic analysis. Large-scale genetic screens …
being well suited to both developmental and genetic analysis. Large-scale genetic screens …
The zebrafish eye—a paradigm for investigating human ocular genetics
Although human epidemiological and genetic studies are essential to elucidate the
aetiology of normal and aberrant ocular development, animal models have provided us with …
aetiology of normal and aberrant ocular development, animal models have provided us with …
A genetic screen for mutations affecting embryogenesis in zebrafish
Systematic genome-wide mutagenesis screens for embryonic phenotypes have been
instrumental in the understanding of invertebrate and plant development. Here, we report …
instrumental in the understanding of invertebrate and plant development. Here, we report …
nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate
JA Lister, CP Robertson, T Lepage… - …, 1999 - journals.biologists.com
We report the isolation and identification of a new mutation affecting pigment cell fate in the
zebrafish neural crest. Homozygous nacre (nac w2) mutants lack melanophores throughout …
zebrafish neural crest. Homozygous nacre (nac w2) mutants lack melanophores throughout …
Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo
DYR Stainier, B Fouquet, JN Chen, KS Warren… - …, 1996 - journals.biologists.com
As part of a large-scale mutagenesis screen of the zebrafish genome, we have identified 58
mutations that affect the formation and function of the cardiovascular system. The …
mutations that affect the formation and function of the cardiovascular system. The …
Zebrafish—As an integrative model for twenty‐first century toxicity testing
NS Sipes, S Padilla, TB Knudsen - Birth Defects Research Part …, 2011 - Wiley Online Library
The zebrafish embryo is a useful small model for investigating vertebrate development
because of its transparency, low cost, transgenic and morpholino capabilities, conservation …
because of its transparency, low cost, transgenic and morpholino capabilities, conservation …
Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function
IA Drummond, A Majumdar, H Hentschel… - …, 1998 - journals.biologists.com
The zebrafish pronephric kidney provides a simplified model of nephron development and
epithelial cell differentiation which is amenable to genetic analysis. The pronephros consists …
epithelial cell differentiation which is amenable to genetic analysis. The pronephros consists …
Early retinal development in the zebrafish, Danio rerio: Light and electron microscopic analyses
EA Schmitt, JE Dowling - Journal of Comparative Neurology, 1999 - Wiley Online Library
The morphological differentiation of the zebrafish retina was analyzed by using light (LM)
and transmission electron (TEM) microscopy between the time of initial ganglion cell …
and transmission electron (TEM) microscopy between the time of initial ganglion cell …
Linking genes to brain, behavior and neurological diseases: what can we learn from zebrafish?
S Guo - Genes, Brain and Behavior, 2004 - Wiley Online Library
How our brain is wired and subsequently generates functional output, ranging from sensing
and locomotion to emotion, decision‐making and learning and memory, remains poorly …
and locomotion to emotion, decision‐making and learning and memory, remains poorly …