[HTML][HTML] Melittin and phospholipase A2: Promising anti-cancer candidates from bee venom

Z Cui, Z Zhou, Z Sun, J Duan, R Liu, C Qi… - Biomedicine & …, 2024 - Elsevier
As the research on cancer-related treatment deepens, integrating traditional therapies with
emerging interventions reveals new therapeutic possibilities. Melittin and phospholipase A2 …

Current status of development and biomedical applications of peptide-based antimicrobial hydrogels

H Qu, Q Yao, T Chen, H Wu, Y Liu, C Wang… - Advances in Colloid and …, 2024 - Elsevier
Microbial contamination poses a serious threat to human life and health. Through the
intersection of material science and modern medicine, advanced bionic hydrogels have …

Delivery strategies for melittin-based cancer therapy

J Zhou, C Wan, J Cheng, H Huang… - ACS Applied Materials …, 2021 - ACS Publications
Melittin (MLT) has been studied preclinically as an anticancer agent based on its broad lytic
effects in multiple tumor types. However, unsatisfactory tissue distribution, hemolysis, rapid …

Recent research progress of biologically active peptides

L Kang, T Han, H Cong, B Yu, Y Shen - Biofactors, 2022 - Wiley Online Library
With the rapid development of molecular biology and biochemical technology, great
progress has been made in the study of peptides. Peptides are easy to digest and absorb …

Nanocarrier system: An emerging strategy for bioactive peptide delivery

X Zhang, X Li, Y Zhao, Q Zheng, Q Wu, Y Yu - Frontiers in Nutrition, 2022 - frontiersin.org
Compared with small-molecule synthetic drugs, bioactive peptides have desirable
advantages in efficiency, selectivity, safety, tolerance, and side effects, which are accepted …

Versatile hydrogel-based drug delivery platform for multimodal cancer therapy from bench to bedside

Y Mei, J Hu, Y Cao, X Gao, L Tang, W Wang - Applied Materials Today, 2024 - Elsevier
Hydrogel exhibits a promising application prospect for multimodal cancer therapy in clinic
compared with other conventional drug delivery platforms, which is predominantly attributed …

Highly in vitro anti-cancer activity of melittin-loaded niosomes on non-small cell lung cancer cells

P Honari, D Shahbazzadeh, M Behdani, KP Bagheri - Toxicon, 2024 - Elsevier
Background Development of promising medicines from natural sources, specially venom, is
of highly necessitated to combat against life-threatening cancers. Non-small cell lung cancer …

Mechanism of peptide self-assembly and its study in biomedicine

X Yang, L Ma, K Lu, D Zhao - The Protein Journal, 2024 - Springer
The development of peptide-based materials is one of the most challenging aspects of
biomaterials research in recent years. The assembly of peptides is mainly controlled by …

[HTML][HTML] Fluoropolymers-mediated efficient biomacromolecule drug delivery

T Song, Y Gao, M Song, J Qian, H Zhang, J Zhou… - Medicine in Drug …, 2022 - Elsevier
Biomacromolecule drugs of nucleic acids and proteins/peptides have occupied growing
share of global pharmaceutical market, but their biomedical application faces substantial …

A helical oncolytic polypeptide with potent membranolytic activity for cancer therapy

X Hu, J Li, Y Zhang, M **ong, H Zhang, Y Yuan - Biomaterials Science, 2023 - pubs.rsc.org
Oncolytic peptides (OLPs) with membranolytic activity show great potential to combat
multidrug-resistant cancer cells. Herein, we report a cationic helical oncolytic polypeptide …