Lactococcus lactis has progressed a long way since its discovery and initial use in dairy
product fermentation, to its present biotechnological applications in genetic engineering for …

Over the past 20 years, a variety of potential adjuvants have been studied to enhance the
effect of oral vaccines in the intestinal mucosal immune system; however, no licensed …

Enteroids are cultured primary intestinal epithelial cells that recapitulate epithelial lineage
development allowing for a more complex and physiologically relevant model for scientific …

Vaccines are one of the greatest medical interventions of all time and have been successful
in controlling and eliminating a myriad of diseases over the past two centuries. Among …

Lactic acid bacteria (LAB) are Gram-positive, acid-tolerant bacteria that have long been
used in food fermentation and are generally recognized as safe (GRAS). LAB are a part of a …

The oral delivery of macromolecules is quite challenging due to environmental insults and
biological barriers encountered along the gastrointestinal (GI) tract. Benefiting from their …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread all over the
world and became a pandemic that named coronavirus disease-2019 (COVID-19). At …

Lactococcus lactis is a promising candidate for the development of mucosal vaccines. More
than 20 years of experimental research supports this immunization approach. In addition …

Gamma-aminobutyrate (GABA) is an important chemical in the pharmaceutical field. GABA-
producing lactic acid bacteria (LAB) offer the opportunity of develo** this health-oriented …

Melanoma is the most aggressive form of skin cancer. Hypoxia is a feature of the tumor
microenvironment that reduces efficacy of immuno-and chemotherapies, resulting in poor …