A growing subset of metalloenzymes activates dioxygen with nonheme diiron active sites to
effect substrate oxidations that range from the hydroxylation of methane and the …

Calcineurin is a eukaryotic Ca2+-and calmodulin-dependent serine/threonine protein
phosphatase. It is a heterodimeric protein consisting of a catalytic subunit calcineurin A …

X-ray absorption Fe− K edge data on ferrous and ferric model complexes have been studied
to establish a detailed understanding of the 1s→ 3d pre-edge feature and its sensitivity to …

Metabolic and signaling biochemical pathways have numerous steps that involve the
hydrolytic cleavage of peptide or phosphate ester bonds. Although both types of bonds are …

Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …

Numerous studies, both in enzymatic and nonenzymatic catalysis, have been undertaken to
understand the way by which metal ions, especially zinc ions, promote the hydrolysis of …

Purple acid phosphatase is a widely distributed non-specific phosphomonoesterase. X-ray
structures of the dimeric 111-kDa Fe (III)-Zn (II) kidney bean purple acid phosphatase …

Kidney bean purple acid phosphatase (KBPAP) is an Fe (III)-Zn (II) metalloenzyme
resembling the mammalian Fe (III)-Fe (II) purple acid phosphatases. The structure of the …

A key question for the understanding of photosynthetic water oxidation is whether the four
oxidizing equivalents necessary to oxidize water to dioxygen are accumulated on the four …

The synthesis, single crystal X-ray crystallographic, magnetic and electrochemical
characterization of eight representative symmetric and unsymmetric complexes as structural …