Highlights•The biofilm formation process and its microenvironmental characteristics are
described.•Biofilm microenvironment-responsive nanoparticles for anti-infection are …

Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

Stubborn biofilm infections pose serious threats to human health due to the persistence,
recurrence, and dramatically magnified antibiotic resistance. Photodynamic therapy has …

As a near-infrared (NIR) adsorbing dye approved by the FDA, indocyanine green (ICG) can
serve as an attractive therapeutic agent to combat biofilm infections through synergistic …

Bacterial infection is a series of pathological changes caused by bacteria invading the host
and interacting with the body. Nowadays, bacterial infection remains a major public health …

Staphylococcus aureus is a highly adaptable opportunistic pathogen that can form biofilms
and generate persister cells, leading to life-threatening infections that are difficult to treat …

This work investigated the antibacterial activity and mechanism of canthin-6-one (CAN) on
Staphylococcus aureus (S. aureus). CAN could inhibit the growth of S. aureus with minimum …

Inflammatory diseases, such as rheumatoid arthritis, periodontitis, chronic obstructive
pulmonary disease, and celiac disease, disrupt the delicate balance between bone …

It is of great importance to develop new strategies to combat antibiotic resistance. Our lab
has discovered halogenated phenazine (HP) analogues that are highly active against …

Bacterial biofilms are surface-attached communities of slow-or non-replicating cells
embedded within a protective matrix of biomolecules. Unlike free-floating planktonic …