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The syndrome we refer to as Hepatic Encephalopathy (HE) was first characterized by a team
of Nobel Prize winning physiologists led by Pavlov and Nencki at the Imperial Institute of …

Background & Aims Hyperammonaemia is central in the pathogenesis of hepatic
encephalopathy. It also has pleiotropic deleterious effects on several organ systems, such …

Background High volume plasma-exchange (HVPE) improves survival in patients with acute
liver failure (ALF), but apprehension regarding volume overload and worsening of cerebral …

Hepatic encephalopathy (HE) is a serious neuropsychiatric complication of cirrhosis and/or
porto-systemic shunting. The clinical symptoms are widely variable, extending from subtle …

Liver failure affects brain function, leading to neurological and psychiatric alterations; such
alterations are referred to as hepatic encephalopathy (HE). Early diagnosis of minimal HE …

Acute-on-chronic liver failure (ACLF) is an increasingly recognised entity encompassing an
acute deterioration of liver function in patients with cirrhosis, which is usually associated with …

Liver failure is a dreaded and often fatal complication that sometimes follows a partial
hepatic resection. This article reviews the definition, incidence, pathogenesis, risk factors …

High circulating ammonia concentrations are common in patients with acute liver failure
(ALF) and are associated with hepatic encephalopathy (HE) and intracranial hypertension …

Cerebral oedema is a devastating consequence of acute liver failure (ALF) and may be
associated with the development of intracranial hypertension and death. In ALF, some …