Emerging role of the brain in the homeostatic regulation of energy and glucose metabolism
E Roh, DK Song, MS Kim - Experimental & molecular medicine, 2016 - nature.com
Accumulated evidence from genetic animal models suggests that the brain, particularly the
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …
hypothalamus, has a key role in the homeostatic regulation of energy and glucose …
AMPK activation: a therapeutic target for type 2 diabetes?
KA Coughlan, RJ Valentine… - … syndrome and obesity …, 2014 - Taylor & Francis
Type 2 diabetes (T2D) is a metabolic disease characterized by insulin resistance, β-cell
dysfunction, and elevated hepatic glucose output. Over 350 million people worldwide have …
dysfunction, and elevated hepatic glucose output. Over 350 million people worldwide have …
Berberine activates thermogenesis in white and brown adipose tissue
Obesity develops when energy intake exceeds energy expenditure. Promoting brown
adipose tissue formation and function increases energy expenditure and hence may …
adipose tissue formation and function increases energy expenditure and hence may …
Transparent, highly stretchable, rehealable, sensing, and fully recyclable ionic conductors fabricated by one‐step polymerization based on a small biological molecule
To date, various stretchable conductors have been fabricated, but simultaneous realization
of the transparency, high stretchability, electrical conductivity, self‐healing capability, and …
of the transparency, high stretchability, electrical conductivity, self‐healing capability, and …
AMPK in health and disease
The function and survival of all organisms is dependent on the dynamic control of energy
metabolism, when energy demand is matched to energy supply. The AMP-activated protein …
metabolism, when energy demand is matched to energy supply. The AMP-activated protein …
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential
KP Shay, RF Moreau, EJ Smith, AR Smith… - Biochimica et Biophysica …, 2009 - Elsevier
Alpha-lipoic acid (LA) has become a common ingredient in multivitamin formulas, anti-aging
supplements, and even pet food. It is well-defined as a therapy for preventing diabetic …
supplements, and even pet food. It is well-defined as a therapy for preventing diabetic …
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular
energy status, and recent data demonstrate that it also plays a critical role in systemic …
energy status, and recent data demonstrate that it also plays a critical role in systemic …
AMPK activators: mechanisms of action and physiological activities
J Kim, G Yang, Y Kim, J Kim, J Ha - Experimental & molecular medicine, 2016 - nature.com
AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which
coordinates metabolic pathways and thus balances nutrient supply with energy demand …
coordinates metabolic pathways and thus balances nutrient supply with energy demand …
Hypothalamic AMPK: a canonical regulator of whole-body energy balance
AMP-activated protein kinase (AMPK) has a major role in the modulation of energy balance.
AMPK is activated in conditions of low energy, increasing energy production and reducing …
AMPK is activated in conditions of low energy, increasing energy production and reducing …
Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential
Background The molecular nature of lipoic acid (LA) clarifies its capability of taking part to a
variety of biochemical reactions where redox state is meaningful. The pivotal action of LA is …
variety of biochemical reactions where redox state is meaningful. The pivotal action of LA is …