Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Relationship between structure and antimicrobial activity of zinc oxide nanoparticles: An overview

B Lallo da Silva, MP Abuçafy… - International journal …, 2019 - Taylor & Francis
The inappropriate use of antimicrobials has resulted in the selection of resistant strains.
Thus, a great number of studies have focused on the investigation of new antimicrobial …

Structural and chemical biology of terpenoid cyclases

DW Christianson - Chemical reviews, 2017 - ACS Publications
The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

Microbial pigments in the food industry—challenges and the way forward

T Sen, CJ Barrow, SK Deshmukh - Frontiers in nutrition, 2019 - frontiersin.org
Develo** new colors for the food industry is challenging, as colorants need to be
compatible with a food flavors, safety, and nutritional value, and which ultimately have a …

Small molecules from the human microbiota

MS Donia, MA Fischbach - Science, 2015 - science.org
BACKGROUND Two developments in distinct fields are converging to create interest in
discovering small molecules from the human microbiome. First, the use of genomics to guide …

Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst

KL Tomlinson, SA Riquelme, SU Baskota, M Drikic… - Cell reports, 2023 - cell.com
Neutrophils are critical in the host defense against Staphylococcus aureus, a major human
pathogen. However, even in the setting of a robust neutrophil response, S. aureus can …

Antibiotics and bacterial resistance in the 21st century

RJ Fair, Y Tor - Perspectives in medicinal chemistry, 2014 - journals.sagepub.com
Dangerous, antibiotic resistant bacteria have been observed with increasing frequency over
the past several decades. In this review the factors that have been linked to this …

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

P Cimermancic, MH Medema, J Claesen, K Kurita… - Cell, 2014 - cell.com
Although biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial
metabolites, our knowledge of their diversity remains limited. Here, we used a novel …

Plant natural products targeting bacterial virulence factors

LN Silva, KR Zimmer, AJ Macedo, DS Trentin - Chemical reviews, 2016 - ACS Publications
Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

Clinical relevance of the ESKAPE pathogens

JN Pendleton, SP Gorman… - Expert review of anti …, 2013 - Taylor & Francis
In recent years, the Infectious Diseases Society of America has highlighted a faction of
antibiotic-resistant bacteria (Enterococcus faecium, Staphylococcus aureus, Klebsiella …