This review covers the diverse topic of neuroendocrine neoplasms (NENs), a relatively rare
and heterogeneous tumor type, comprising~ 2% of all malignancies, with a prevalence of< …

Context.—The 5th edition of the World Health Organization classification of digestive system
tumors discusses several advancements and developments in understanding the etiology …

The classification of neuroendocrine neoplasms (NENs) differs between organ systems and
currently causes considerable confusion. A uniform classification framework for NENs at any …

The neuroendocrine carcinoma of the gastrointestinal system (GIS-NEC) is a rare but highly
malignant neoplasm. We analyzed 115 cases using whole-genome/exome sequencing …

Background As studies on gastrointestinal neuroendocrine carcinoma (WHO G3)(GI-NEC)
are limited, we reviewed clinical data to identify predictive and prognostic markers for …

Neuroendocrine tumors are a heterogeneous group of tumors originating in various
anatomic locations. The management of this disease poses a significant challenge because …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms are classified as low‐grade,
intermediate‐grade, and high‐grade tumors based on morphologic criteria and the …

Data on gastroenteropancreatic neuroendocrine neoplasms (NEN) G3 (well-differentiated
neuroendocrine tumors (NET G3) and neuroendocrine carcinoma (NEC)) are limited. We …

Purpose: Patients with pancreatic neuroendocrine neoplasm grade-3 (PanNEN-G3) show
variable responses to platinum-based chemotherapy. Recent studies indicated that PanNEN …

Background: In the pancreas, poorly differentiated neuroendocrine carcinomas include
small cell carcinoma and large cell neuroendocrine carcinoma and are rare; data regarding …