Fast scan cyclic voltammetry: Chemical sensing in the brain and beyond

JG Roberts, LA Sombers - Analytical chemistry, 2017 - pmc.ncbi.nlm.nih.gov
In this review we describe the electroanalytical method known as fast-scan cyclic
voltammetry (FSCV), how it has advanced over the years, and in what way (s) it is impacting …

Electrochemical analysis of neurotransmitters

ES Bucher, RM Wightman - Annual review of analytical …, 2015 - annualreviews.org
Chemical signaling through the release of neurotransmitters into the extracellular space is
the primary means of communication between neurons. More than four decades ago, Ralph …

Biocompatible PEDOT: Nafion composite electrode coatings for selective detection of neurotransmitters in vivo

RF Vreeland, CW Atcherley, WS Russell… - Analytical …, 2015 - ACS Publications
A Nafion and poly (3, 4-ethylenedioxythiophene)(PEDOT) containing composite polymer
has been electropolymerized on carbon-fiber microelectrodes with the goal of creating a …

Challenges and strategies faced in the electrochemical biosensing analysis of neurochemicals in vivo: A review

J Chen, X Ding, D Zhang - Talanta, 2024 - Elsevier
Our brain is an intricate neuromodulatory network, and various neurochemicals, including
neurotransmitters, neuromodulators, gases, ions, and energy metabolites, play important …

Analytical techniques in neuroscience: recent advances in imaging, separation, and electrochemical methods

M Ganesana, ST Lee, Y Wang, BJ Venton - Analytical chemistry, 2017 - ACS Publications
How do we understand neuronal signaling in the brain, how neurons control behavior, or
how signaling malfunctions during disease? Neuroscientists might take two approaches …

Carbon nanotubes grown on metal microelectrodes for the detection of dopamine

C Yang, CB Jacobs, MD Nguyen, M Ganesana… - Analytical …, 2016 - ACS Publications
Microelectrodes modified with carbon nanotubes (CNTs) are useful for the detection of
neurotransmitters because the CNTs enhance sensitivity and have electrocatalytic effects …

Tracking tonic dopamine levels in vivo using multiple cyclic square wave voltammetry

Y Oh, ML Heien, C Park, YM Kang, J Kim… - Biosensors and …, 2018 - Elsevier
For over two decades, fast-scan cyclic voltammetry (FSCV) has served as a reliable
analytical method for monitoring dopamine release in near real-time in vivo. However …

In vivo ambient serotonin measurements at carbon-fiber microelectrodes

A Abdalla, CW Atcherley, P Pathirathna… - Analytical …, 2017 - ACS Publications
The mechanisms that control extracellular serotonin levels in vivo are not well-defined. This
shortcoming makes it very challenging to diagnose and treat the many psychiatric disorders …

Direct in vivo electrochemical detection of resting dopamine using poly (3, 4-ethylenedioxythiophene)/carbon nanotube functionalized microelectrodes

IM Taylor, NA Patel, NC Freedman… - Analytical …, 2019 - ACS Publications
Dopamine (DA) is a monoamine neurotransmitter responsible for the maintenance of a
variety of vital life functions. In vivo DA signaling occurs over multiple time scales, from …

A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies

PJ Grahn, GW Mallory, OU Khurram, BM Berry… - Frontiers in …, 2014 - frontiersin.org
Current strategies for optimizing deep brain stimulation (DBS) therapy involve multiple
postoperative visits. During each visit, stimulation parameters are adjusted until desired …