Copy number variation in domestication

ZN Lye, MD Purugganan - Trends in Plant Science, 2019 - cell.com
Domesticated plants have long served as excellent models for studying evolution. Many
genes and mutations underlying important domestication traits have been identified, and …

Ancestry-inclusive dog genomics challenges popular breed stereotypes

K Morrill, J Hekman, X Li, J McClure, B Logan… - Science, 2022 - science.org
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Grey wolf genomic history reveals a dual ancestry of dogs

A Bergström, DWG Stanton, UH Taron, L Frantz… - Nature, 2022 - nature.com
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and
they remained widespread throughout the last Ice Age when many other large mammal …

Man's best friend in life and death: scientific perspectives and challenges of dog brain banking

S Sándor, K Czeibert, A Salamon, E Kubinyi - GeroScience, 2021 - Springer
Biobanking refers to the systematic collection, storage, and distribution of pre-or post-
mortem biological samples derived from volunteer donors. The demand for high-quality …

​ Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs

KL Moon, HJ Huson, K Morrill, MS Wang, X Li… - Science, 2023 - science.org
We reconstruct the phenotype of Balto, the heroic sled dog renowned for transporting
diphtheria antitoxin to Nome, Alaska, in 1925, using evolutionary constraint estimates from …

Identification of high-confidence structural variants in domesticated rainbow trout using whole-genome sequencing

S Liu, G Gao, RM Layer, GH Thorgaard… - Frontiers in …, 2021 - frontiersin.org
Genomic structural variants (SVs) are a major source of genetic and phenotypic variation but
have not been investigated systematically in rainbow trout (Oncorhynchus mykiss), an …

Inbreeding depression causes reduced fecundity in Golden Retrievers

ET Chu, MJ Simpson, K Diehl, RL Page, AJ Sams… - Mammalian …, 2019 - Springer
Inbreeding depression has been demonstrated to impact vital rates, productivity, and
performance in human populations, wild and endangered species, and in recent years, the …

Five genetic variants explain over 70% of hair coat pheomelanin intensity variation in purebred and mixed breed domestic dogs

AJ Slavney, T Kawakami, MK Jensen, TC Nelson… - PLoS …, 2021 - journals.plos.org
In mammals, the pigment molecule pheomelanin confers red and yellow color to hair, and
the intensity of this coloration is caused by variation in the amount of pheomelanin. Domestic …

[HTML][HTML] Many direct-to-consumer canine genetic tests can identify the breed of purebred dogs

HM Rando, K Graim, G Hampikian… - Journal of the American …, 2024 - Am Vet Med Assoc
Many direct-to-consumer canine genetic tests can identify the breed of purebred dogs in:
Journal of the American Veterinary Medical Association Volume 262 Issue 5 (2024) Jump to …

Genome wide association study with imputed whole genome sequence data identifies a 431 kb risk haplotype on CFA18 for congenital laryngeal paralysis in Alaskan …

K Srikanth, DJF von Pfeil, BJ Stanley, C Griffitts… - Genes, 2022 - mdpi.com
Congenital laryngeal paralysis (CLP) is an inherited disorder that affects the ability of the
dog to exercise and precludes it from functioning as a working sled dog. Though CLP is …