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Synthesis and glycosidation of anomeric halides: evolution from early studies to modern methods of the 21st century
Advances in synthetic carbohydrate chemistry have dramatically improved access to
common glycans. However, many novel methods still fail to adequately address challenges …
common glycans. However, many novel methods still fail to adequately address challenges …
Automated chemical oligosaccharide synthesis: novel approach to traditional challenges
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …
more accessible. However, many current methods still rely heavily upon specialized …
Synthetic microbial consortia: from systematic analysis to construction and applications
H Song, MZ Ding, XQ Jia, Q Ma, YJ Yuan - Chemical Society Reviews, 2014 - pubs.rsc.org
Synthetic biology is an emerging research field that focuses on using rational engineering
strategies to program biological systems, conferring on them new functions and behaviours …
strategies to program biological systems, conferring on them new functions and behaviours …
Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules
Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …
Application of carbohydrates in approved small molecule drugs: A review
H Jiang, X Qin, Q Wang, Q Xu, J Wang, Y Wu… - European Journal of …, 2021 - Elsevier
Carbohydrates are an important energy source and play numerous key roles in all living
organisms. Carbohydrates chemistry involved in diagnosis and treatment of diseases has …
organisms. Carbohydrates chemistry involved in diagnosis and treatment of diseases has …
Synthesis of N‐Glycosides by Silver‐Assisted Gold Catalysis
S Chakraborty, B Mishra, P Kumar Das… - Angewandte Chemie …, 2023 - Wiley Online Library
The synthesis of N‐glycosides from stable glycosyl donors in a catalytic fashion is still
challenging, though they exist ubiquitously in DNA, RNA, glycoproteins, and other biological …
challenging, though they exist ubiquitously in DNA, RNA, glycoproteins, and other biological …
Mechanism of chemical glycosylation: focus on the mode of activation and departure of anomeric leaving groups
SC Ranade, AV Demchenko - Journal of Carbohydrate Chemistry, 2013 - Taylor & Francis
Many glycosyl donors used in chemical glycosylation are too stable to undergo spontaneous
glycosylation. Hence, the first key step of practically every glycosylation reaction is the …
glycosylation. Hence, the first key step of practically every glycosylation reaction is the …
Therapeutic potential of pectin and its derivatives in chronic diseases
Non-communicable diseases (NCDs) are described as a collection of chronic diseases that
do not typically develop from an acute infection, have long-term health effects, and …
do not typically develop from an acute infection, have long-term health effects, and …
The structural biology of enzymes involved in natural product glycosylation
Covering: up to 2012 The glycosylation of microbial natural products often dramatically
influences the biological and/or pharmacological activities of the parental metabolite. Over …
influences the biological and/or pharmacological activities of the parental metabolite. Over …
Post-screening characterisation and in vivo evaluation of an anti-inflammatory polysaccharide fraction from Eucommia ulmoides
Q Li, Y Feng, W He, L Wang, R Wang, L Dong… - Carbohydrate …, 2017 - Elsevier
We report here the discovery of a polysaccharide, namely EUP1, with anti-inflammatory
activity from the herb of Eucommia ulmoides Oliv. We separated three polysaccharide …
activity from the herb of Eucommia ulmoides Oliv. We separated three polysaccharide …