Machine learning for antimicrobial peptide identification and design
Artificial intelligence (AI) and machine learning (ML) models are being deployed in many
domains of society and have recently reached the field of drug discovery. Given the …
domains of society and have recently reached the field of drug discovery. Given the …
Microbiome dynamics: a paradigm shift in combatting infectious diseases
Infectious diseases have long posed a significant threat to global health and require
constant innovation in treatment approaches. However, recent groundbreaking research has …
constant innovation in treatment approaches. However, recent groundbreaking research has …
Artificial intelligence-driven antimicrobial peptide discovery
Antimicrobial peptides (AMPs) emerge as promising agents against antimicrobial resistance,
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
providing an alternative to conventional antibiotics. Artificial intelligence (AI) revolutionized …
Peptides from non-immune proteins target infections through antimicrobial and immunomodulatory properties
Encrypted peptides (EPs) have been recently described as a new class of antimicrobial
molecules. They have been found in numerous organisms and have been proposed to have …
molecules. They have been found in numerous organisms and have been proposed to have …
Challenges in computational discovery of bioactive peptides in'omics data
Peptides have a plethora of activities in biological systems that can potentially be exploited
biotechnologically. Several peptides are used clinically, as well as in industry and …
biotechnologically. Several peptides are used clinically, as well as in industry and …
Antimicrobial peptides and their druggability, bio-safety, stability, and resistance
The excessive and often indiscriminate use of antibiotics in many areas of human activities
has caused a widespread antibiotic resistance, which poses a major threat to the public …
has caused a widespread antibiotic resistance, which poses a major threat to the public …
A catalog of small proteins from the global microbiome
Small open reading frames (smORFs) shorter than 100 codons are widespread and perform
essential roles in microorganisms, where they encode proteins active in several cell …
essential roles in microorganisms, where they encode proteins active in several cell …
[HTML][HTML] AI in infectious diseases: The role of datasets
C de la Fuente-Nunez - Drug resistance updates: reviews and …, 2024 - pmc.ncbi.nlm.nih.gov
AI in infectious diseases: The role of datasets - PMC Skip to main content Here's how you know
Official websites use .gov A .gov website belongs to an official government organization in the …
Official websites use .gov A .gov website belongs to an official government organization in the …
[HTML][HTML] Assessing fecal metaproteomics workflow and small protein recovery using DDA and DIA PASEF mass spectrometry
A Wang, EEF Fekete, M Creskey… - Microbiome …, 2024 - pmc.ncbi.nlm.nih.gov
Aim: This study aims to evaluate the impact of experimental workflow on fecal
metaproteomic observations, including the recovery of small and antimicrobial proteins often …
metaproteomic observations, including the recovery of small and antimicrobial proteins often …
[HTML][HTML] Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance
T Coxe, RK Azad - Antibiotics, 2023 - mdpi.com
In his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial
resistance (AMR) if the necessary precautions were not taken diligently. As the growing …
resistance (AMR) if the necessary precautions were not taken diligently. As the growing …