Nanoparticulate delivery systems for antiviral drugs

D Lembo, R Cavalli - Antiviral Chemistry and Chemotherapy, 2010 - journals.sagepub.com
Nanomedicine opens new therapeutic avenues for attacking viral diseases and for
improving treatment success rates. Nanoparticulate-based systems might change the …

Poly (lactide-co-glycolide)-based micro and nanoparticles for the controlled drug delivery of vitamins

M Stevanovic, D Uskokovic - Current nanoscience, 2009 - ingentaconnect.com
Controlled drug delivery systems and polymeric carriers have undergone significant
development in recent years. Polymers like polylactides (PLA), polyglycolides (PGA), poly …

Potential roles of the glass transition temperature of PLGA microparticles in drug release kinetics

K Park, A Otte, F Sharifi, J Garner… - Molecular …, 2020 - ACS Publications
Poly (lactic-co-glycolic acid)(PLGA) has been used for long-acting injectable drug delivery
systems for more than 30 years. The factors affecting the properties of PLGA formulations …

Evaluation of ciprofloxacin-loaded Eudragit® RS100 or RL100/PLGA nanoparticles

K Dillen, J Vandervoort, G Van den Mooter… - International journal of …, 2006 - Elsevier
The objective of present study was to prepare positively charged ciprofloxacin-loaded
nanoparticles providing a controlled release formulation. The particles were prepared by …

The potential of using biodegradable microspheres in retinal diseases and other intraocular pathologies

R Herrero-Vanrell, I Bravo-Osuna… - Progress in retinal and …, 2014 - Elsevier
Pathologies affecting the posterior segment of the eye are one of the major causes of
blindness in developed countries and are becoming more prevalent due to the increase in …

Effects of process and formulation parameters on characteristics and internal morphology of poly (d, l-lactide-co-glycolide) microspheres formed by the solvent …

S Mao, Y Shi, L Li, J Xu, A Schaper, T Kissel - European journal of …, 2008 - Elsevier
Taking ABT627 as a hydrophobic model drug, poly-(lactic-co-glycolic acid)(PLGA)
microspheres were prepared by an emulsion solvent evaporation method. Various process …

Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage

AC Amrite, SP Ayalasomayajula… - … & visual science, 2006 - iovs.arvojournals.org
purpose. To determine whether celecoxib inhibits VEGF secretion from ARPE-19 cells and
to investigate further the safety and effectiveness of periocular celecoxib-poly (lactide-co …

Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir

Ž Pavelić, N Škalko-Basnet, J Filipović-Grčić… - Journal of controlled …, 2005 - Elsevier
Design of a liposome delivery system for vaginal administration of acyclovir, able to provide
sustained release and improved bioavailability of the encapsulated drug for the local …

Atorvastatin-eluting contact lenses: effects of molecular imprinting and sterilization on drug loading and release

AF Pereira-da-Mota, M Vivero-Lopez, A Topete… - Pharmaceutics, 2021 - mdpi.com
Statins are receiving increasing attention in the ophthalmic field. Their activity as 3-hydroxy-
3-methylglutaryl–CoA (HMG–CoA) reductase inhibitors is clinically used to regulate …

Gamma sterilization of pharmaceuticals—a review of the irradiation of excipients, active pharmaceutical ingredients, and final drug product formulations

F Hasanain, K Guenther, WM Mullett… - PDA journal of …, 2014 - journal.pda.org
Sterilization by gamma irradiation has shown a strong applicability for a wide range of
pharmaceutical products. Due to the requirement for terminal sterilization where possible in …