Since the first description of RNA interference (RNAi) in animals less than a decade ago,
there has been rapid progress towards its use as a therapeutic modality against human …

Small interfering RNA (siRNA) is a potential method of gene silencing to target specific
genes. Although the US Food and Drug Administration (FDA) has approved multiple siRNA …

The capacity to efficiently transduce nondividing cells, shuttle large genetic payloads, and
maintain stable long-term transgene expression are attributes that have brought lentiviral …

Small interfering RNA (siRNA) has garnered much attention in recent years as a promising
avenue for cancer gene therapy due to its ability to silence disease-related genes. Effective …

Currently, there is no cure and no preventive vaccine for HIV/AIDS. Combination
antiretroviral therapy has dramatically improved treatment, but it has to be taken for a …

Background RNA interference (RNAi) is a regulatory mechanism conserved in higher
eukaryotes. The RNAi pathway generates small interfering RNA (siRNA) or micro RNA …

Aptamers are oligonucleotides evolved in vitro or in nature to bind target ligands with high
affinity and specificity. They are emerging as powerful tools in the fields of therapeutics, drug …

RNA interference (RNAi) is a post‐transcriptional gene silencing mechanism induced by
small interfering RNAs (siRNAs) and micro‐RNAs (miRNAs), and has proved to be one of …