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Circadian gene variants in cancer
NM Kettner, CA Katchy, L Fu - Annals of medicine, 2014 - Taylor & Francis
Humans as diurnal beings are active during the day and rest at night. This daily oscillation of
behavior and physiology is driven by an endogenous circadian clock not environmental …
behavior and physiology is driven by an endogenous circadian clock not environmental …
DEC1 and DEC2 crosstalk between circadian rhythm and tumor progression
F Sato, UK Bhawal, T Yoshimura… - Journal of …, 2016 - pmc.ncbi.nlm.nih.gov
Clock genes, major regulators of circadian rhythm, are involved in tumor progression. We
have shown that clock genes basic helix-loop-helix (BHLH) transcription factors …
have shown that clock genes basic helix-loop-helix (BHLH) transcription factors …
HIF1A protein expression is correlated with clinical features in gastric cancer: an updated systematic review and meta-analysis
S Nam, Y Lee - Scientific Reports, 2024 - nature.com
To elucidate the correlation of HIF1A with clinicopathologic characteristics in patients with
gastric cancer (GC), we conducted a systematic review and meta-analysis. We searched …
gastric cancer (GC), we conducted a systematic review and meta-analysis. We searched …
Non-circadian aspects of BHLHE40 cellular function in cancer
While many genes specifically act as oncogenes or tumor suppressors, others are tumor
promoters or suppressors in a context-dependent manner. Here we will review the basic …
promoters or suppressors in a context-dependent manner. Here we will review the basic …
The distinct expression patterns of claudin-2,-6, and− 11 between human gastric neoplasms and adjacent non-neoplastic tissues
Z Lin, X Zhang, Z Liu, Q Liu, L Wang, Y Lu, Y Liu… - Diagnostic …, 2013 - Springer
Background Cancers have a multifactorial etiology a part of which is genetic. Recent data
indicate that expression of the tight junction claudin proteins is involved in the etiology and …
indicate that expression of the tight junction claudin proteins is involved in the etiology and …
Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma
XP Wang, QX Wang, HP Lin, N Chang - Food & Function, 2017 - pubs.rsc.org
Curcumin, a derivative from the dried rhizome of curcuma longa, has been proven to
possess anti-tumor effects. However, the detailed molecular mechanisms have not been …
possess anti-tumor effects. However, the detailed molecular mechanisms have not been …
Expression characteristics of CDC20 in gastric cancer and its correlation with poor prognosis
ZY Ding, HR Wu, JM Zhang… - International journal of …, 2014 - pmc.ncbi.nlm.nih.gov
The cell division cycle 20 homolog (CDC20) expression is increased in diverse human
cancers and plays a vital role in tumorigenesis and progression. However, the clinical …
cancers and plays a vital role in tumorigenesis and progression. However, the clinical …
[HTML][HTML] Prognostic impact of Ki-67 in patients with gastric cancer—the importance of depth of invasion and histologic differentiation
GH Ko, SI Go, WS Lee, JH Lee, SH Jeong, YJ Lee… - Medicine, 2017 - journals.lww.com
Ki-67 protein is a cellular marker for proliferation. The role of Ki-67 as a prognostic
biomarker has not been established in gastric cancer. The present study was performed to …
biomarker has not been established in gastric cancer. The present study was performed to …
The role of hypoxic signalling in metastasis: towards translating knowledge of basic biology into novel anti-tumour strategies
J Araos, JP Sleeman, BK Garvalov - Clinical & experimental metastasis, 2018 - Springer
Hypoxia is a characteristic feature of many cancer types, which ensues when the growth of a
tumour outpaces its oxygen supply. The cellular response to reduced oxygen tension is …
tumour outpaces its oxygen supply. The cellular response to reduced oxygen tension is …
Weiqi Decoction Attenuated Chronic Atrophic Gastritis with Precancerous Lesion through Regulating Microcirculation Disturbance and HIF‐1α Signaling Pathway
J Yin, J Yi, C Yang, B Xu, J Lin, H Hu… - Evidence‐Based …, 2019 - Wiley Online Library
Aim. Chronic atrophic gastritis (CAG), the precancerous lesions of gastric cancer, plays an
important role in the stepwise process of gastric cancer. The ancient Chinese medicine …
important role in the stepwise process of gastric cancer. The ancient Chinese medicine …