Introduction Multiple Sclerosis (MS) is a chronic neurodegenerative disorder that affects the
central nervous system (CNS) and results in progressive clinical disability and cognitive …

The neuropsychological aspects of multiple sclerosis (MS) have evolved over the past three
decades. What was once thought to be a rare occurrence, cognitive dysfunction is now …

Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …

Abstract See Chard and Miller (doi: 10.1093/brain/awv354) for a scientific commentary on
this article. Grey matter atrophy is common in multiple sclerosis. However, in contrast with …

Objective To determine whether brain atrophy and lesion volumes predict subsequent 10
year clinical evolution in multiple sclerosis (MS). Design From eight MAGNIMS (MAGNetic …

Purpose To apply quantitative susceptibility map** (QSM) in the basal ganglia of patients
with multiple sclerosis (MS) and relate the findings to R2* map** with regard to the …

Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Objectives To identify MRI biomarkers associated with long-term disability progression in
patients with multiple sclerosis (MS), and to define the rate of evolution of global, tissue …

Objective To investigate the relationship among cortical radiologic changes, the number of
early relapses (ERs), and the long-term course of multiple sclerosis (MS). Methods In this …

Purpose To investigate the association between the development of thalamic and cortical
atrophy and the conversion to clinically definite multiple sclerosis (CDMS) in patients with …