Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins

A Alonso, M Greenlee, J Matts, J Kline, KJ Davis… - …, 2015 - Wiley Online Library
Sumoylation is a powerful regulatory system that controls many of the critical processes in
the cell, including DNA repair, transcriptional regulation, nuclear transport, and DNA …

Functional characterization of two flavone synthase II members in citrus

J Zheng, C Zhao, Z Liao, X Liu, Q Gong… - Horticulture …, 2023 - academic.oup.com
Polymethoxylated flavones (PMFs), the main form of flavones in citrus, are derived from the
flavone branch of the flavonoid biosynthesis pathway. Flavone synthases (FNSs) are …

Hydrogen peroxide sensitivity connects the activity of COX5A and NPR3 to the regulation of YAP1 expression

S Takallou, M Hajikarimlou, M Al‐gafari… - The FASEB …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are among the most severe types of cellular stressors with
the ability to damage essential cellular biomolecules. Excess levels of ROS are correlated …

DBP7 and YRF1-6 Are Involved in Cell Sensitivity to LiCl by Regulating the Translation of PGM2 mRNA

SK Jagadeesan, M Al-Gafari, J Wang… - International Journal of …, 2023 - mdpi.com
Lithium chloride (LiCl) has been widely researched and utilized as a therapeutic option for
bipolar disorder (BD). Several pathways, including cell signaling and signal transduction …

Lithium chloride sensitivity in yeast and regulation of translation

M Hajikarimlou, K Hunt, G Kirby, S Takallou… - International Journal of …, 2020 - mdpi.com
For decades, lithium chloride (LiCl) has been used as a treatment option for those living with
bipolar disorder (BD). As a result, many studies have been conducted to examine its mode …

Sensitivity of yeast to lithium chloride connects the activity of YTA6 and YPR096C to translation of structured mRNAs

M Hajikarimlou, H Moteshareie, K Omidi, M Hooshyar… - PLoS …, 2020 - journals.plos.org
Lithium Chloride (LiCl) toxicity, mode of action and cellular responses have been the subject
of active investigations over the past decades. In yeast, LiCl treatment is reported to reduce …

Deacetylation of H4 lysine16 affects acetylation of lysine residues in histone H3 and H4 and promotes transcription of constitutive genes

A Ray, P Khan, R Nag Chaudhuri - Epigenetics, 2021 - Taylor & Francis
Histone modification map of H4 N-terminal tail residues in Saccharomyces cerevisiae
reveals the prominence of lysine acetylation. Previous reports have indicated the importance …

A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1

JW Westerbeck, N Pasupala, M Guillotte… - Molecular biology of …, 2014 - Am Soc Cell Biol
The Slx5/Slx8 heterodimer constitutes a SUMO-targeted ubiquitin ligase (STUbL) with an
important role in SUMO-targeted degradation and SUMO-dependent signaling. This STUbL …

Oxidative stress‐induced YAP1 expression is regulated by NCE102, CDA2, and BCS1

S Takallou, M Hajikarimlou, M Al‐gafari… - The FEBS …, 2024 - Wiley Online Library
Maintaining cellular homeostasis in the face of stress conditions is vital for the overall well‐
being of an organism. Reactive oxygen species (ROS) are among the most potent cellular …

Growth-based determination and biochemical confirmation of genetic requirements for protein degradation in Saccharomyces cerevisiae

SG Watts, JJ Crowder, SZ Coffey… - Journal of visualized …, 2015 - pmc.ncbi.nlm.nih.gov
Regulated protein degradation is crucial for virtually every cellular function. Much of what is
known about the molecular mechanisms and genetic requirements for eukaryotic protein …