Recent advances in poor HIV immune reconstitution: what will the future look like?

W Zhang, L Ruan - Frontiers in Microbiology, 2023 - frontiersin.org
Combination antiretroviral therapy has demonstrated proved effectiveness in suppressing
viral replication and significantly recovering CD4+ T cell count in HIV type-1 (HIV-1)-infected …

Nanoparticle-based strategies to target HIV-infected cells

D Soundararajan, LN Ramana, P Shankaran… - Colloids and Surfaces B …, 2022 - Elsevier
Antiretroviral drugs employed for the treatment of human immunodeficiency virus (HIV)
infections have remained largely ineffective due to their poor bioavailability, numerous …

Therapeutic roles of CAR T cells in infectious diseases: Clinical lessons learnt from cancer

M Mohammadi, M Akhoundi, S Malih… - Reviews in Medical …, 2022 - Wiley Online Library
Cancer immunotherapy has made improvements due to the advances in chimaeric antigen
receptor (CAR) T cell development, offering a promising treatment option for patients who …

Estimates of prevalence, time-trend, and association of smoking in adults living with HIV, HBV, and HCV (NHANES 1999–2018)

J Yang, JL Lin, J Liu, XW Jiang, H Zhang, L Peng - Scientific Reports, 2022 - nature.com
Although the smoking rate of human immunodeficiency virus (HIV), hepatitis B virus (HBV) or
hepatitis C virus (HCV) infected people was much higher than that of the general population …

Pharmacokinetic drug-drug interactions involving antiretroviral agents: an update

X Yu, L Zhao, Z Yuan, Y Li - Current Drug Metabolism, 2023 - ingentaconnect.com
Antiretroviral therapy is the recognized treatment for human immunodeficiency virus (HIV)
infection involving several antiviral agents. Even though highly active antiretroviral therapy …

Exploring potential associations between the human microbiota and reservoir of latent HIV

N Marín-Sánchez, R Paredes, A Borgognone - Retrovirology, 2024 - Springer
Background The rapid establishment and persistence of latent HIV-1 reservoirs is one of the
main obstacles towards an HIV cure. While antiretroviral therapy supresses viral replication …

CXCR4 Is a Potential Target for Anti-HIV Gene Therapy

AK Prokopovich, IS Litvinova, AE Zubkova… - International Journal of …, 2024 - mdpi.com
The human immunodeficiency virus (HIV) epidemic is a global issue. The estimated number
of people with HIV is 39,000,000 to date. Antiviral therapy is the primary approach to treat …

Strategies for HIV-1 suppression through key genes and cell therapy

A Sorokina, E Anchakova, E Dashinimaev - Frontiers in Medicine, 2023 - frontiersin.org
Human immunodeficiency virus type 1 (HIV-1) remains a significant challenge for global
public health as limited therapeutic options are available for HIV-infected individuals …

Exploring the potential of structural modeling and molecular docking for efficient siRNA screening: A promising approach to Combat viral mutants, with a focus on HIV …

M Nematian, Z Noormohammadi, P Rahimi… - Biochemical and …, 2024 - Elsevier
RNA interference (RNAi) holds immense potential for sequence-specific downregulation of
disease-related genes. Small interfering RNA (siRNA) therapy has made remarkable strides …

[PDF][PDF] Exosomes in viral infection: Effects for pathogenesis and treatment strategies

F Heidari, R Seyedebrahimi, P Yang, M Farsani… - Biocell, 2023 - cdn.techscience.cn
Exosomes are small vesicles that carry molecules from one cell to another. They have many
features that make them interesting for research, such as their stability, low immunogenicity …