The E26 transformation specific (ETS) family comprises 28 transcription factors, the majority
of which are involved in tumor initiation and development. Serving as a group of functionally …

A significant portion of mammalian proteomes is secreted to the extracellular space to fulfill
crucial roles in cell-to-cell communication. To best recapitulate the intricate and multi-faceted …

Inflammation is a common condition of prostate tissue, whose impact on carcinogenesis is
highly debated. Microbial colonization is a well-documented cause of a small percentage of …

Prostate cancer (PCa) is annually the most frequently diagnosed cancer in the male
population. To date, the diagnostic path for PCa detection includes the dosage of serum …

The functional activation of the androgen receptor (AR) and its interplay with the aberrant
Hh/Gli cascade are pivotal in the progression of castration-resistant prostate cancer (CRPC) …

Retinoic acid (RA) signaling is a master regulator of vertebrate development with crucial
roles in body axis orientation and tissue differentiation, including in the reproductive system …

Background Some studies confirmed that erythroblast transformation‐specific‐related gene
(ERG) may be a pathogenic factor of oral squamous cell carcinoma (OSCC). However, the …

Organoid modeling is a powerful, robust and efficient technology faithfully preserving
physiological and pathological characteristics of tissues of origin. Recently, substantial …

Objective To explore the mechanisms of miR-196b affecting the progression of lung
adenocarcinoma (LUAD). Methods The expression level of miR-196b in LUAD tissues was …

目的探究miR-196b 影响肺腺癌(lung adenocarcinoma, LUAD) 进展的机制. 方法通过TCGA
数据库分析miR-196b 在LUAD 组织中的表达水**, 利用TargetScan 预测其下游靶基因并用双 …