Metagenomics-a guide from sampling to data analysis

T Thomas, J Gilbert, F Meyer - Microbial informatics and experimentation, 2012 - Springer
Metagenomics applies a suite of genomic technologies and bioinformatics tools to directly
access the genetic content of entire communities of organisms. The field of metagenomics …

An introduction to the analysis of shotgun metagenomic data

TJ Sharpton - Frontiers in plant science, 2014 - frontiersin.org
Environmental DNA sequencing has revealed the expansive biodiversity of microorganisms
and clarified the relationship between host-associated microbial communities and host …

Kraken: ultrafast metagenomic sequence classification using exact alignments

DE Wood, SL Salzberg - Genome biology, 2014 - Springer
Kraken is an ultrafast and highly accurate program for assigning taxonomic labels to
metagenomic DNA sequences. Previous programs designed for this task have been …

Critical assessment of metagenome interpretation—a benchmark of metagenomics software

A Sczyrba, P Hofmann, P Belmann, D Koslicki… - Nature …, 2017 - nature.com
Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome
data, but a lack of consensus about benchmarking complicates performance assessment …

CLARK: fast and accurate classification of metagenomic and genomic sequences using discriminative k-mers

R Ounit, S Wanamaker, TJ Close, S Lonardi - BMC genomics, 2015 - Springer
Background The problem of supervised DNA sequence classification arises in several fields
of computational molecular biology. Although this problem has been extensively studied, it is …

Functional diversity within the simple gut microbiota of the honey bee

P Engel, VG Martinson… - Proceedings of the …, 2012 - National Acad Sciences
Animals living in social communities typically harbor a characteristic gut microbiota
important for nutrition and pathogen defense. Accordingly, in the gut of the honey bee, Apis …

The Human Microbiome Project: a community resource for the healthy human microbiome

D Gevers, R Knight, JF Petrosino, K Huang… - 2012 - journals.plos.org
The Human Microbiome Project: A Community Resource for the Healthy Human Microbiome |
PLOS Biology Skip to main content Advertisement PLOS Biology Browse Current Issue Journal …

Metagenomic species profiling using universal phylogenetic marker genes

S Sunagawa, DR Mende, G Zeller… - Nature …, 2013 - nature.com
To quantify known and unknown microorganisms at species-level resolution using shotgun
sequencing data, we developed a method that establishes metagenomic operational …

Critical assessment of metagenome interpretation: the second round of challenges

F Meyer, A Fritz, ZL Deng, D Koslicki, TR Lesker… - Nature …, 2022 - nature.com
Evaluating metagenomic software is key for optimizing metagenome interpretation and focus
of the Initiative for the Critical Assessment of Metagenome Interpretation (CAMI). The CAMI II …

Metagenomics: tools and insights for analyzing next-generation sequencing data derived from biodiversity studies

A Oulas, C Pavloudi, P Polymenakou… - … and biology insights, 2015 - journals.sagepub.com
Advances in next-generation sequencing (NGS) have allowed significant breakthroughs in
microbial ecology studies. This has led to the rapid expansion of research in the field and …