[HTML][HTML] Protein–protein interaction prediction with deep learning: A comprehensive review

F Soleymani, E Paquet, H Viktor, W Michalowski… - Computational and …, 2022 - Elsevier
Most proteins perform their biological function by interacting with themselves or other
molecules. Thus, one may obtain biological insights into protein functions, disease …

Protein–RNA interaction prediction with deep learning: structure matters

J Wei, S Chen, L Zong, X Gao, Y Li - Briefings in bioinformatics, 2022 - academic.oup.com
Protein–RNA interactions are of vital importance to a variety of cellular activities. Both
experimental and computational techniques have been developed to study the interactions …

Diffdock-pp: Rigid protein-protein docking with diffusion models

MA Ketata, C Laue, R Mammadov, H Stärk… - arxiv preprint arxiv …, 2023 - arxiv.org
Understanding how proteins structurally interact is crucial to modern biology, with
applications in drug discovery and protein design. Recent machine learning methods have …

Machine learning solutions for predicting protein–protein interactions

R Casadio, PL Martelli… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Proteins are “social molecules.” Recent experimental evidence supports the notion that
large protein aggregates, known as biomolecular condensates, affect structurally and …

Evaluating representation learning on the protein structure universe

AR Jamasb, A Morehead, CK Joshi, Z Zhang, K Didi… - Ar**v, 2024 - pmc.ncbi.nlm.nih.gov
We introduce ProteinWorkshop, a comprehensive benchmark suite for representation
learning on protein structures with Geometric Graph Neural Networks. We consider large …

Graphein-a Python library for geometric deep learning and network analysis on protein structures and interaction networks

AR Jamasb, R Viñas, EJ Ma, C Harris, K Huang, D Hall… - bioRxiv, 2020 - biorxiv.org
Geometric deep learning has well-motivated applications in the context of biology, a domain
where relational structure in datasets can be meaningfully leveraged. Currently, efforts in …

Knowledge-augmented Graph Machine Learning for Drug Discovery: From Precision to Interpretability

Z Zhong, D Mottin - Proceedings of the 29th ACM SIGKDD Conference …, 2023 - dl.acm.org
Conventional Artificial Intelligence models are heavily limited in handling complex
biomedical structures (such as 2D or 3D protein and molecule structures) and providing …

Graphein-a python library for geometric deep learning and network analysis on biomolecular structures and interaction networks

A Jamasb, R Viñas Torné, E Ma, Y Du… - Advances in …, 2022 - proceedings.neurips.cc
Geometric deep learning has broad applications in biology, a domain where relational
structure in data is often intrinsic to modelling the underlying phenomena. Currently, efforts …

Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

Exploiting hierarchical interactions for protein surface learning

Y Lin, L Pan, Y Li, Z Liu, X Li - IEEE Journal of Biomedical and …, 2024 - ieeexplore.ieee.org
Predicting interactions between proteins is one of the most important yet challenging
problems in structural bioinformatics. Intrinsically, potential function sites in protein surfaces …