Applications of capillary electromigration methods for separation and analysis of proteins (2017–mid 2021)–a review

S Štěpánová, V Kašička - Analytica Chimica Acta, 2022 - Elsevier
This paper provides a detailed overview of relevant developments in separation and
analysis of proteins by capillary electromigration (CE) methods in the period 2017–mid …

Advances in capillary electrophoresis mass spectrometry for metabolomics

T Soga - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Capillary electrophoresis mass spectrometry (CE-MS) is now regarded as a powerful tool for
the comprehensive analysis of low-molecular-weight charged metabolites. Over the past …

Applications of capillary electrophoresis for biopharmaceutical product characterization

R Kumar, A Guttman, AS Rathore - Electrophoresis, 2022 - Wiley Online Library
Capillary electrophoresis (CE), after being introduced several decades ago, has carved out
a niche for itself in the field of analytical characterization of biopharmaceutical products. It …

Insights from capillary electrophoresis approaches for characterization of monoclonal antibodies and antibody drug conjugates in the period 2016–2018

A Lechner, J Giorgetti, R Gahoual, A Beck… - … of Chromatography B, 2019 - Elsevier
Monoclonal antibodies (mAbs) and their related products as antibody-drug-conjugates
(ADCs) or biosimilars represent a constantly growing class of molecules therapeutic proteins …

Spray-capillary-based capillary electrophoresis mass spectrometry for metabolite analysis in single cells

L Huang, M Fang, KA Cupp-Sutton, Z Wang… - Analytical …, 2021 - ACS Publications
Single-cell capillary electrophoresis mass spectrometry (CE-MS) is a promising platform to
analyze cellular contents and probe cell heterogeneity. However, current single-cell CE-MS …

Establishment of measurement traceability for peptide and protein quantification through rigorous purity assessment—a review

RD Josephs, G Martos, M Li, L Wu, JE Melanson… - Metrologia, 2019 - iopscience.iop.org
The health of their populations and efficient health care systems are of critical importance to
the economic and social well-being of nations. Accurate and comparable peptide/protein …

Analysis of monoclonal antibodies by capillary electrophoresis: sample preparation, separation, and detection

M Dadouch, Y Ladner, C Perrin - Separations, 2021 - mdpi.com
Therapeutic monoclonal antibodies (mAbs) are dominating the biopharmaceutical field due
to the fact of their high specificity in the treatment of diverse diseases. Nevertheless, mAbs …

Capillary electrophoresis as a sample separation step to mass spectrometry analysis: a primer

BH Lapizco-Encinas, YV Zhang, PP Gqamana… - TrAC Trends in …, 2023 - Elsevier
Capillary electrophoresis (CE) is a separation technique that offers high resolution, great
sensitivity, and short processing times. Mass spectrometry (MS) accurately characterizes …

Advances in capillary electrophoresis-mass spectrometry for cell analysis

W Zhou, B Zhang, Y Liu, C Wang, W Sun, W Li… - TrAC Trends in …, 2019 - Elsevier
Mass spectrometry has become a powerful tool in the field of bioanalysis. The combination
of capillary electrophoresis with mass spectrometry (CE-MS) offers fast and high-resolution …

Structure and effective charge characterization of proteins by a mobility capillary electrophoresis based method

W Zhang, H Wu, R Zhang, X Fang, W Xu - Chemical science, 2019 - pubs.rsc.org
Measuring the conformations and effective charges of proteins in solution is critical for
investigating protein bioactivity, but their rapid analysis remains a challenging problem …