Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies

M Solmi, J Radua, M Olivola, E Croce, L Soardo… - Molecular …, 2022 - nature.com
Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

Neurocognitive functioning in individuals at clinical high risk for psychosis: a systematic review and meta-analysis

A Catalan, GS De Pablo, C Aymerich, S Damiani… - JAMA …, 2021 - jamanetwork.com
Importance Neurocognitive functioning is a potential biomarker to advance detection,
prognosis, and preventive care for individuals at clinical high risk for psychosis (CHR-P) …

Preventive psychiatry: a blueprint for improving the mental health of young people

P Fusar‐Poli, CU Correll, C Arango, M Berk… - World …, 2021 - Wiley Online Library
Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …

Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis

GS De Pablo, J Radua, J Pereira, I Bonoldi… - JAMA …, 2021 - jamanetwork.com
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Meta-analytic prevalence of comorbid mental disorders in individuals at clinical high risk of psychosis: the case for transdiagnostic assessment

M Solmi, L Soardo, S Kaur, M Azis, A Cabras… - Molecular …, 2023 - nature.com
Comorbid mental disorders in subjects at clinical high risk for psychosis (CHR-P) may
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …

Prenatal and perinatal risk and protective factors for psychosis: a systematic review and meta-analysis

C Davies, G Segre, A Estradé, J Radua… - The Lancet …, 2020 - thelancet.com
Background Prenatal and perinatal insults are implicated in the aetiopathogenesis of
psychotic disorders but the consistency and magnitude of their associations with psychosis …

What causes psychosis? An umbrella review of risk and protective factors

J Radua, V Ramella‐Cravaro, JPA Ioannidis… - World …, 2018 - Wiley Online Library
Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and
protective factors have been suggested. This umbrella review aimed to classify the strength …

Improving outcomes of first‐episode psychosis: an overview

P Fusar‐Poli, PD McGorry, JM Kane - World psychiatry, 2017 - Wiley Online Library
Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …

Integrated mental health services for the developmental period (0 to 25 years): a critical review of the evidence

P Fusar-Poli - Frontiers in psychiatry, 2019 - frontiersin.org
Background: The developmental period from 0 to 25 years is a vulnerable time during which
children and young people experience many psychosocial and neurobiological changes …

Annual Research Review: Prevention of psychosis in adolescents–systematic review and meta‐analysis of advances in detection, prognosis and intervention

A Catalan, G Salazar de Pablo… - Journal of Child …, 2021 - Wiley Online Library
Background The clinical high‐risk state for psychosis (CHR‐P) paradigm has facilitated the
implementation of psychosis prevention into clinical practice; however, advancements in …