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Molecular photoswitches in aqueous environments
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …
precision, using light as external stimulus, and hence are ideal tools for different research …
The cell biology of primary cell walls during salt stress
Salt stress simultaneously causes ionic toxicity, osmotic stress, and oxidative stress, which
directly impact plant growth and development. Plants have developed numerous strategies …
directly impact plant growth and development. Plants have developed numerous strategies …
Stress physiology of lactic acid bacteria
Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …
Mechanomicrobiology: how bacteria sense and respond to forces
Microorganisms have evolved to thrive in virtually any terrestrial and marine environment,
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …
exposing them to various mechanical cues mainly generated by fluid flow and pressure as …
Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Touch, tension, and transduction–the function and regulation of Piezo ion channels
J Wu, AH Lewis, J Grandl - Trends in biochemical sciences, 2017 - cell.com
In 2010, two proteins, Piezo1 and Piezo2, were identified as the long-sought molecular
carriers of an excitatory mechanically activated current found in many cells. This discovery …
carriers of an excitatory mechanically activated current found in many cells. This discovery …
Structure-based membrane dome mechanism for Piezo mechanosensitivity
YR Guo, R MacKinnon - elife, 2017 - elifesciences.org
Mechanosensitive ion channels convert external mechanical stimuli into electrochemical
signals for critical processes including touch sensation, balance, and cardiovascular …
signals for critical processes including touch sensation, balance, and cardiovascular …
Molecular machines for the control of transmembrane transport
Nature embeds some of its molecular machinery, including ion pumps, within lipid bilayer
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …
TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells
The proteins that form the permeation pathway of mechanosensory transduction channels in
inner-ear hair cells have not been definitively identified. Genetic, anatomical, and …
inner-ear hair cells have not been definitively identified. Genetic, anatomical, and …
Membrane proteins bind lipids selectively to modulate their structure and function
Previous studies have established that the folding, structure and function of membrane
proteins are influenced by their lipid environments,,,,,, and that lipids can bind to specific …
proteins are influenced by their lipid environments,,,,,, and that lipids can bind to specific …