The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

Metrics for green chemistry are to identify features of a chemical process that adhere to the
green chemistry principles. Several metrics are available for assessing analytical method …

This review article summarizes recent developments of green chemistry and sustainability
metrics with a focus on the pharmaceutical industry. We discuss synergies and …

The use of polyvinyl chloride (PVC) plastic bags leads to environmental pollution and waste
residues caused by low recycling and slow degradation rates, which is inconsistent with the …

The private sector must play a central role in advancing the Sustainable Development Goals
(SDGs). To fulfill their duty, businesses must rely on accurate methodologies for measuring …

Chemistry contributes to virtually every aspect of modern life, from the production of fuels,
food, and clean drinking water to medicines, cleaners, personal care, as well as a host of …

Development of a scalable route for the synthesis of nirmatrelvir, the novel SARS-CoV-2 3C-
like protease inhibitor discovered in 2020 by Pfizer scientists, was initiated shortly thereafter …

The challenges and opportunities of develo** API manufacturing processes continue to
grow. Molecular complexity of APIs is increasing, process development times are …

Small molecule therapeutics represent the majority of the FDA-approved drugs. Yet, many
attractive targets are poorly tractable by small molecules, generating a need for new …