The mechanisms by which animals adapt to an ever‐changing environment have long
fascinated scientists. Different forces, conveying information regarding various aspects of the …

Orexin-A and orexin-B are hypothalamic peptides that act via two G protein-coupled
receptors, named orexin type 1 and type 2 receptors (OX1-Rs and OX2-Rs). The most …

In mammals, hypocretin/orexin (HCRT) neuropeptides are important sleep–wake regulators
and HCRT deficiency causes narcolepsy. In addition to fragmented wakefulness, narcoleptic …

Knockdown of orexin/hypocretin 2 receptor (Orx 2) in the basolateral amygdala (BLA) affects
anxious and depressive behavior. We use a new behavioral paradigm, the Stress …

It is extremely important for the health to understand the regulatory mechanisms of energy
expenditure. These regulatory mechanisms play a central role in the pathogenesis of body …

In response to changes in society and thus the marketplace, we need a vision for the future
of our animal industries, including both on-farm and off-farm activities, that is “clean, green …

Hypothalmic orexin/hypocretin (Orx) neurons in the lateral and dorsomedial perifornical
region (LH-DMH/PeF) innervate broadly throughout the brain, and receive similar inputs …

Calorie restriction (CR) is a common approach to inducing negative energy balance.
Recently, time-restricted feeding (TRF), which involves consuming food within specific time …

Although recently discovered, orexins have been rapidly established as important
neuropeptides in regulating physiological processes including food intake, sleep/wake …

Background Observational findings suggest that patients with narcolepsy are at higher risk
for cardiovascular diseases (CVDs), but the potential causal relationship between …