Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Recent advances in the synthesis of indanes and indenes

B Gabriele, R Mancuso, L Veltri - Chemistry–A European …, 2016 - Wiley Online Library
Indanes and indenes are among the most important carbocycles. Many indane and indene
derivatives have shown important pharmacological activities, and the indane and indene …

Recent progress in organocatalytic asymmetric domino transformations

T Chanda, JCG Zhao - Advanced Synthesis & Catalysis, 2018 - Wiley Online Library
Sustainability in chemical synthesis is a major aspect of the current synthetic endeavors and,
therefore, mimicking the biological process in the laboratory nowadays has the highest …

Asymmetric Organocatalytic Synthesis of 3-Diarylmethine-Substituted Oxindoles Bearing a Quaternary Stereocenter via 1,6-Conjugate Addition to para-Quinone …

K Zhao, Y Zhi, A Wang, D Enders - ACS Catalysis, 2016 - ACS Publications
A highly stereoselective organocatalytic 1, 6-conjugate addition of 3-substituted oxindoles to
para-quinone methides to construct all-carbon quaternary stereocenters is described. In the …

Recent Catalytic Asymmetric Syntheses of 3, 3‐Disubstituted Indolin‐2‐ones and 2, 2‐Disubstituted Indolin‐3‐ones

R Dalpozzo - Advanced Synthesis & Catalysis, 2017 - Wiley Online Library
Disubstituted oxindoles represent an important family of bioactive compounds and synthetic
derivatives that mimic natural products. The construction of the asymmetric quaternary …

Enantioselective syntheses of indanes: from organocatalysis to C–H functionalization

C Borie, L Ackermann, M Nechab - Chemical Society Reviews, 2016 - pubs.rsc.org
The indanyl core is ubiquitous in a large variety of drugs and natural products. Importantly,
the ever-increasing demand for chiral catalysts bearing this scaffold calls for state of the art …

Recent advances in organocatalytic cascade reactions toward the formation of quaternary stereocenters

F Vetica, RM de Figueiredo, M Orsini, D Tofani… - …, 2015 - thieme-connect.com
This review provides the authors' selection of recent publications that highlight the
increasing efforts to develop valuable organocatalytic domino/tandem/cascade reactions as …

On the mechanism of bifunctional squaramide‐catalyzed organocatalytic Michael addition: a protonated catalyst as an oxyanion hole

B Kótai, G Kardos, A Hamza, V Farkas… - … A European Journal, 2014 - Wiley Online Library
A joint experimental–theoretical study of a bifunctional squaramide‐amine‐catalyzed
Michael addition reaction between 1, 3‐dioxo nucleophiles and nitrostyrene has been …

The Squaramide‐Catalyzed 1,3‐Dipolar Cycloaddition of Nitroalkenes with N‐2,2,2‐Trifluoroethylisatin Ketimines: An Approach for the Synthesis of 5 …

Q Sun, X Li, J Su, L Zhao, M Ma, Y Zhu… - Advanced Synthesis …, 2015 - Wiley Online Library
A Cinchona alkaloid‐derived squaramide‐catalyzed asymmetric cycloaddition of
trfluoromethyl‐containing azomethine ylides with β‐nitroalkenes was realized under mild …

Recent developments in the synthesis of chiral compounds with quaternary centers by organocatalytic cascade reactions

L Tian, YC Luo, XQ Hu, PF Xu - Asian Journal of Organic …, 2016 - Wiley Online Library
Quaternary carbon stereocenters are present in a wide variety of organic compounds and
drug molecules. Highly enantioselective construction of such quaternary carbon …