Leveraging diet to engineer the gut microbiome

M Wolter, ET Grant, M Boudaud, A Steimle… - Nature reviews …, 2021 - nature.com
Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …

Gut microbiota, leaky gut, and autoimmune diseases

A Christovich, XM Luo - Frontiers in immunology, 2022 - frontiersin.org
With the rising prevalence of autoimmune diseases, the role of the environment, specifically
the gut microbiota, in disease development has grown to be a major area of study. Recent …

Gut microbiota composition is related to AD pathology

BJH Verhaar, HMA Hendriksen, FA de Leeuw… - Frontiers in …, 2022 - frontiersin.org
Introduction Several studies have reported alterations in gut microbiota composition of
Alzheimer's disease (AD) patients. However, the observed differences are not consistent …

An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants

DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

Neurodegenerative and neurodevelopmental diseases and the gut-brain axis: The potential of therapeutic targeting of the microbiome

B Bicknell, A Liebert, T Borody, G Herkes… - International journal of …, 2023 - mdpi.com
The human gut microbiome contains the largest number of bacteria in the body and has the
potential to greatly influence metabolism, not only locally but also systemically. There is an …

The role of fecal microbiota transplantation in the treatment of neurodegenerative diseases: a review

JAT Matheson, RMD Holsinger - International Journal of Molecular …, 2023 - mdpi.com
Neurodegenerative diseases are highly prevalent but poorly understood, and with few
treatment options despite decades of intense research, attention has recently shifted toward …

Targeting the gut to treat multiple sclerosis

L Ghezzi, C Cantoni, GV **et… - The Journal of clinical …, 2021 - Am Soc Clin Investig
The gut-brain axis (GBA) refers to the complex interactions between the gut microbiota and
the nervous, immune, and endocrine systems, together linking brain and gut functions …

[HTML][HTML] Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression

L Lin, K Zhang, Q **ong, J Zhang, B Cai, Z Huang… - Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

[HTML][HTML] Fecal microbiota transplantation: Emerging applications in autoimmune diseases

R Yang, Z Chen, J Cai - Journal of Autoimmunity, 2023 - Elsevier
Both genetic susceptibility and environmental factors are important contributors to
autoimmune disease pathogenesis. As an environmental factor, the gut microbiome plays a …

The gut-brain axis in multiple sclerosis. Is its dysfunction a pathological trigger or a consequence of the disease?

B Parodi, N Kerlero de Rosbo - Frontiers in immunology, 2021 - frontiersin.org
A large and expending body of evidence indicates that the gut-brain axis likely plays a
crucial role in neurological diseases, including multiple sclerosis (MS). As a whole, the gut …