To update and integrate the recommendations for ankylosing spondylitis and the
recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial …

OBJECTIVES: The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
program was initiated by the International Organization for the Study of Inflammatory Bowel …

Objectives To update the Assessment of SpondyloArthritis international Society (ASAS)-
EULAR recommendations for the management of axial spondyloarthritis (axSpA). Methods …

Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

Background Gut-selective blockade of lymphocyte trafficking by vedolizumab may constitute
effective treatment for ulcerative colitis. Methods We conducted two integrated randomized …

Background The efficacy of vedolizumab, an α4β7 integrin antibody, in Crohn's disease is
unknown. Methods In an integrated study with separate induction and maintenance trials …

Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

There has been a revolution in nanotechnology and nanomedicine. Since 1980, there has
been a remarkable increase in approved nano-based pharmaceutical products. These novel …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …