[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics

DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …

Human T-cell lymphotropic virus type 1 (HTLV-1) proposed vaccines: a systematic review of preclinical and clinical studies

N Seighali, A Shafiee, MA Rafiee, D Aminzade… - BMC Infectious …, 2023 - Springer
Background Numerous vaccination research experiments have been conducted on non-
primate hosts to prevent or control HTLV-1 infection. Therefore, reviewing recent …

Development of a tetravalent subunit vaccine against dengue virus through a vaccinomics approach

A Basheer, SB Jamal, B Alzahrani… - Frontiers in …, 2023 - frontiersin.org
Dengue virus infection (DVI) is a mosquito-borne disease that can lead to serious morbidity
and mortality. Dengue fever (DF) is a major public health concern that affects approximately …

Reverse vaccinology approaches to design a potent multiepitope vaccine against the HIV whole genome: immunoinformatic, bioinformatics, and molecular dynamics …

A Hashempour, N Khodadad, S Akbarinia… - BMC Infectious …, 2024 - Springer
Substantial advances have been made in the development of promising HIV vaccines to
eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes …

[HTML][HTML] Immunoinformatics Design of a Multiepitope Vaccine (MEV) Targeting Streptococcus mutans: A Novel Computational Approach

RS Naorem, BD Pangabam, SS Bora, C Fekete… - Pathogens, 2024 - mdpi.com
Dental caries, a persistent oral health challenge primarily linked to Streptococcus mutans,
extends its implications beyond dental decay, affecting over 4 billion individuals globally …

[HTML][HTML] HTLV-1 vaccination Landscape: Current developments and challenges

A Letafati, M Bahari, OS Ardekani, NN Jazi, A Nikzad… - Vaccine: X, 2024 - Elsevier
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that is distinguished for its
correlation to myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell …

Immunoinformatic analysis of the whole proteome for vaccine design: An application to Clostridium perfringens

LF Soto, AC Romaní, G Jiménez-Avalos… - Frontiers in …, 2022 - frontiersin.org
Clostridium perfringens is a dangerous bacterium and known biological warfare weapon
associated with several diseases, whose lethal toxins can produce necrosis in humans …

Multi-epitope vaccines, from design to expression; an in silico approach

B Mortazavi, A Molaei, NA Fard - Human Immunology, 2024 - Elsevier
The development of vaccines against a wide range of infectious diseases and pathogens
often relies on multi-epitope strategies that can effectively stimulate both humoral and …

Advancing PEDV Vaccination: Comparison between Inactivated and Flagellin N-Terminus-Adjuvanted Subunit Vaccines

A Murtaza, NT Hoa, D Dieu-Huong, H Afzal, MH Tariq… - Vaccines, 2024 - mdpi.com
Vaccinations can serve as an important preventive measure against the porcine epidemic
diarrhea (PED) virus that currently threatens the swine industry. This study focuses on the …

Map** potential vaccine candidates predicted by VaxiJen for different viral pathogens between 2017–2021—a sco** review

Z Salod, O Mahomed - Vaccines, 2022 - mdpi.com
Reverse vaccinology (RV) is a promising alternative to traditional vaccinology. RV focuses
on in silico methods to identify antigens or potential vaccine candidates (PVCs) from a …