The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

To curb the high cost of drug development, there is an urgent need to develop more
predictive tissue models using human cells to determine drug efficacy and safety in advance …

On-demand, local delivery of drug molecules to target tissues provides a means for effective
drug dosing while reducing the adverse effects of systemic drug delivery. This work explores …

Three‐dimensional porous scaffolds play a pivotal role in tissue engineering and
regenerative medicine by functioning as biomimetic substrates to manipulate cellular …

Myocardial infarction (MI) leads to a multi-phase reparative process at the site of damaged
heart that ultimately results in the formation of non-conductive fibrous scar tissue. Despite …

The heart is one of the most vital organs in the human body, which actively pumps the blood
through the vascular network to supply nutrients to as well as to extract wastes from all other …

Abstract 3D printing is a technology that allows the fabrication of structures with arbitrary
geometries and heterogeneous material properties. The application of this technology to …

The development of diversified biomaterials in tissue engineering has been promoted by
growing research into carbon-based nanomaterials. Usually, ideal scaffold materials should …

Background Cell behavior is the key to tissue regeneration. Given the fact that most of the
cells used in tissue engineering are anchorage-dependent, their behavior including …