Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …

In the past decade, substantial advances have been made in understanding the biology of
tumour-associated macrophages (TAMs), and their clinical relevance is emerging. A …

Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …

Cancer immunology and immunotherapy are driving forces of research and development in
oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent …

In cancer patients, dendritic cells (DCs) in tumor-draining lymph nodes can present antigens
to naive T cells in ways that break immunological tolerance. The clonally expanded progeny …

Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Epithelial ovarian cancer (EOC) is among the top five causes of cancer-related death in
women, largely reflecting early, prediagnosis dissemination of malignant cells to the …

Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation,
trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested …

Tumorigenesis embodies the formation of a heterotypic tumour microenvironment (TME)
that, among its many functions, enables the evasion of T cell-mediated immune responses …

Macrophages are immune cells that originate from embryogenesis or from the differentiation
of monocytes. They can adopt numerous phenotypes depending on their origin, tissue …