Platelet-neutrophil interplay: insights into neutrophil extracellular trap (NET)-driven coagulation in infection

AZ Zucoloto, CN Jenne - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Well established for their central role in hemostasis, platelets have increasingly been
appreciated as immune cells in recent years. This emerging role should not come as a …

[HTML][HTML] Extracellular heat shock proteins and cancer: New perspectives

Z Albakova, MKS Siam, PK Sacitharan… - Translational …, 2021 - Elsevier
Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …

Platelet innate immune receptors and TLRs: a double-edged sword

T Ebermeyer, F Cognasse, P Berthelot… - International journal of …, 2021 - mdpi.com
Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

Immunothrombosis in COVID-19: implications of neutrophil extracellular traps

B Bautista-Becerril, R Campi-Caballero… - Biomolecules, 2021 - mdpi.com
SARS-CoV-2 is a member of the family of coronaviruses associated with severe outbreaks of
respiratory diseases in recent decades and is the causative agent of the COVID-19 …

The role of platelets in heat-related illness and heat-induced coagulopathy

T Iba, J Helms, M Levi, JH Levy - Thrombosis research, 2023 - Elsevier
Heat-related illness is becoming more problematic due to ongoing global warming. Heat-
related injury causes systemic inflammation and coagulopathy, due to leukocyte, platelet …

Autophagy, molecular chaperones, and unfolded protein response as promoters of tumor recurrence

B Alhasan, M Mikeladze, I Guzhova… - Cancer and Metastasis …, 2023 - Springer
Tumor recurrence is a paradoxical function of a machinery, whereby a small proportion of
the cancer cell population enters a resistant, dormant state, persists long-term in this …

New insights into the role and therapeutic potential of HSP70 in diabetes

AA de Oliveira, VO Mendoza, S Rastogi… - Pharmacological …, 2022 - Elsevier
Emerging evidence indicates that HSP70 represents a key mechanism in the
pathophysiology of β-cell dysfunction, insulin resistance, and various diabetic complications …

Platelet toll-like receptors are crucial sensors of infectious danger moieties

H Hamzeh-Cognasse, P Berthelot, B Tardy, B Pozzetto… - Platelets, 2018 - Taylor & Francis
In addition to their haemostatic role and function in the repair of damaged vascular
epithelium, platelets play a defensive role in innate immunity, having the capacity to produce …

The pro-tumorigenic role of chemotherapy-induced extracellular hsp70 from breast cancer cells via intratumoral macrophages

M Yamaguchi-Tanaka, K Takagi, Y Miki, A Sato… - Cancers, 2023 - mdpi.com
Simple Summary Resistance to chemotherapy is an important problem to be solved in
breast cancer research. Tumor-associated macrophages (TAMs) contribute to breast cancer …

Mortalin is a distinct bio-marker and prognostic factor in serous ovarian carcinoma

M Xu, T **, L Chen, X Zhang, G Zhu, Q Wang, Z Lin - Gene, 2019 - Elsevier
This study focused on mortalin expression and its relevance to the prognosis in serous
ovarian carcinoma, mortalin modulated cell malignant proliferation and EMT progression via …