Review of osteoradionecrosis of the jaw: radiotherapy modality, technique, and dose as risk factors

E Topkan, A Kucuk, E Somay, B Yilmaz… - Journal of Clinical …, 2023 - mdpi.com
Radiotherapy (RT) or concurrent chemoradiotherapy (CCRT) is the cornerstone of organ-
sparing or adjuvant therapy for nearly all head and neck cancers. Unfortunately, aggressive …

Osteoradionecrosis: Exposing the evidence not the bone

AJ Frankart, MJ Frankart, B Cervenka, AL Tang… - International Journal of …, 2021 - Elsevier
Osteoradionecrosis is a relatively rare but potentially morbid and costly complication of
radiation therapy for head and neck cancer. Multidisciplinary diagnosis and treatment are …

Risk factors for osteoradionecrosis of the jaw in patients with head and neck squamous cell carcinoma

H Kubota, D Miyawaki, N Mukumoto, T Ishihara… - Radiation …, 2021 - Springer
Background To evaluate factors associated with osteoradionecrosis of the jaw (ORNJ) in
patients with head and neck squamous cell carcinoma (HNSCC), focusing on jaw-related …

Osteoradionecrosis of the mandible after radiotherapy for head and neck cancer: risk factors and dose-volume correlations

S Aarup-Kristensen, CR Hansen, L Forner… - Acta …, 2019 - Taylor & Francis
Background: The project aimed at determining the incidence of mandibular
osteoradionecrosis (ORN) after radiotherapy, possible risk factors, and mandibular dose …

International guideline on dose prioritization and acceptance criteria in radiation therapy planning for nasopharyngeal carcinoma

AW Lee, WT Ng, JJ Pan, CL Chiang, SS Poh… - International Journal of …, 2019 - Elsevier
Purpose The treatment of nasopharyngeal carcinoma requires high radiation doses. The
balance of the risks of local recurrence owing to inadequate tumor coverage versus the …

[HTML][HTML] Empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck cancer patients treated with pencil-beam-scanning …

Y Yang, OM Muller, SE Schild, M Bues, M Fatyga… - Frontiers in …, 2022 - frontiersin.org
Purpose To retrospectively investigate empirical relative biological effectiveness (RBE) for
mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with …

[HTML][HTML] Osteoradionecrosis after postoperative radiotherapy for oral cavity cancer: a retrospective cohort study

MM Möring, H Mast, EB Wolvius, GM Verduijn, SF Petit… - Oral Oncology, 2022 - Elsevier
Objective Osteoradionecrosis (ORN) is a severe late complication after radiotherapy but
current knowledge on ORN risks in the setting of postoperative radiotherapy (PORT) is …

[HTML][HTML] Radiotherapy controversies and prospective in head and neck cancer: a literature-based critical review

F De Felice, A Polimeni, V Valentini, O Brugnoletti… - Neoplasia, 2018 - Elsevier
In treating head and neck cancer (HNC), the objectives are provided for best functional
results and minimal risk of serious complications. The choice of appropriate management …

[HTML][HTML] Normal Tissue Complication Probability (NTCP) prediction model for osteoradionecrosis of the mandible in patients with head and neck cancer after radiation …

LV van Dijk, AA Abusaif, J Rigert, MA Naser… - International Journal of …, 2021 - Elsevier
Purpose Osteoradionecrosis (ORN) of the mandible represents a severe, debilitating
complication of radiation therapy (RT) for head and neck cancer (HNC). At present, no …

Research frontiers in oral toxicities of cancer therapies: Osteoradionecrosis of the jaws

FKL Spijkervet, MT Brennan, DE Peterson… - JNCI …, 2019 - academic.oup.com
The deleterious effects of head and neck radiation on bone, with osteoradionecrosis (ORN)
as the major disabling side effect of head and neck cancer treatment, are difficult to prevent …