The increasing number of bacterial infections globally that do not respond to any available
antibiotics indicates a need to invest in—and ensure access to—new antibiotics, vaccines …

Streptococcus pneumoniae has a complex relationship with its obligate human host. On the
one hand, the pneumococci are highly adapted commensals, and their main reservoir on the …

Background Pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b
(Hib) vaccine are now used in most countries. To monitor global and regional progress …

Summary In 2013, a Lancet Infectious Diseases Commission described the state of
antimicrobial resistance worldwide. Since then, greater awareness of the public health …

Background Routine immunisation with pneumococcal conjugate vaccines (PCV7/10/13)
has reduced invasive pneumococcal disease (IPD) due to vaccine serotypes significantly …

Background Pneumonia is the leading cause of mortality in pediatric population. The
etiology of pneumonia in this population is variable and changes according to age and …

When to update COVID-19 vaccine composition | Nature Medicine Skip to main content Thank
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Background Invasive pneumococcal disease remains an important health priority owing to
increasing disease incidence caused by pneumococci expressing non-vaccine serotypes …

Background Bacterial bloodstream infection is a common cause of morbidity and mortality in
sub-Saharan Africa, yet few facilities are able to maintain long-term surveillance. The Malawi …

Meningitis is an inflammation of the meninges and subarachnoid space that can also involve
the brain cortex and parenchyma. It can be acquired spontaneously in the community …