Quantitative metabolomics based on gas chromatography mass spectrometry: status and perspectives
MM Koek, RH Jellema, J van der Greef, AC Tas… - Metabolomics, 2011 - Springer
Metabolomics involves the unbiased quantitative and qualitative analysis of the complete set
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …
of metabolites present in cells, body fluids and tissues (the metabolome). By analyzing …
Advanced chemometric and data handling tools for GCŨGC-TOF-MS: Application of chemometrics and related advanced data handling in chemical separations
Comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GC×
GC-MS) has become a mature technique. GC× GC-MS can now be used to conduct large …
GC-MS) has become a mature technique. GC× GC-MS can now be used to conduct large …
[PDF][PDF] Multidimensional gas chromatography: advances in instrumentation, chemometrics, and applications
(GC) methods is an indispensable tool in the analytical chemist's tool box. A myriad of fields
of study rely upon the application of GC methods to address an ever growing demand to …
of study rely upon the application of GC methods to address an ever growing demand to …
Cardiac-specific deletion of acetyl CoA carboxylase 2 prevents metabolic remodeling during pressure-overload hypertrophy
Rationale: Decreased fatty acid oxidation (FAO) with increased reliance on glucose are
hallmarks of metabolic remodeling that occurs in pathological cardiac hypertrophy and is …
hallmarks of metabolic remodeling that occurs in pathological cardiac hypertrophy and is …
Recent developments in the application of comprehensive two-dimensional gas chromatography
M Adahchour, J Beens, UAT Brinkman - Journal of Chromatography A, 2008 - Elsevier
The literature on comprehensive two-dimensional gas chromatography (GC× GC) is
reviewed, with emphasis on application-oriented studies published in the period 2004 …
reviewed, with emphasis on application-oriented studies published in the period 2004 …
Recent advances in GC× GC and chemometrics to address emerging challenges in nontargeted analysis
Pioneered by Liu and Phillips in 1991, 1 comprehensive twodimensional (2D) gas
chromatography (GC× GC) has become an indispensable technique for the separation and …
chromatography (GC× GC) has become an indispensable technique for the separation and …
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry
(GC× GC–TOFMS) coupled with pattern recognition methods was applied to analyze plasma …
(GC× GC–TOFMS) coupled with pattern recognition methods was applied to analyze plasma …
Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes
WB Dunn - Physical biology, 2008 - iopscience.iop.org
The functional levels of biological cells or organisms can be separated into the genome,
transcriptome, proteome and metabolome. Of these the metabolome offers specific …
transcriptome, proteome and metabolome. Of these the metabolome offers specific …
Chemometrics, comprehensive two-dimensional gas chromatography and “omics” sciences: Basic tools and recent applications
Abstract The advent of Comprehensive Two-dimensional Gas Chromatography (GC× GC)
as a practical and accessible analytical tool had a considerable impact on analytical …
as a practical and accessible analytical tool had a considerable impact on analytical …
Current and emerging mass-spectrometry technologies for metabolomics
M Bedair, LW Sumner - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
Mass spectrometry (MS) has secured a central role in metabolomics that is predicted to grow
based upon continuous developments and improvements in MS technologies. This article …
based upon continuous developments and improvements in MS technologies. This article …