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Delivery and performance of surfactant replacement therapies to treat pulmonary disorders
Lung surfactant is crucial for optimal pulmonary function throughout life. An absence or
deficiency of surfactant can affect the surfactant pool leading to respiratory distress. Even if …
deficiency of surfactant can affect the surfactant pool leading to respiratory distress. Even if …
Nanovesicle aerosols as surfactant therapy in lung injury
Acute lung injury causes inactivation of pulmonary surfactant due to leakage of albumin and
other markers. Current surfactants are ineffective in this condition and are instilled …
other markers. Current surfactants are ineffective in this condition and are instilled …
Surface patterning of single-walled carbon nanotubes enhances their perturbation on a pulmonary surfactant monolayer: frustrated translocation and bilayer …
The pulmonary surfactant monolayer (PSM) is a complex material lining the air–water
interface of lung alveoli to avoid its collapse by reducing surface tension. Once external …
interface of lung alveoli to avoid its collapse by reducing surface tension. Once external …
Mitigation of hydrochloric acid (HCl)-induced lung injury in mice by aerosol therapy of surface-active nanovesicles containing antioxidant and anti-inflammatory drugs
Acute lung injury leading to alveolar inflammation and surfactant dysfunction remains a
medical challenge. Surface-active lipid nanovesicles of 200–250 nm size with antioxidant D …
medical challenge. Surface-active lipid nanovesicles of 200–250 nm size with antioxidant D …