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Insights into glomerular filtration and albuminuria
Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
Cell biology of the glomerular podocyte
H Pavenstadt, W Kriz, M Kretzler - Physiological reviews, 2003 - journals.physiology.org
Glomerular podocytes are highly specialized cells with a complex cytoarchitecture. Their
most prominent features are interdigitated foot processes with filtration slits in between …
most prominent features are interdigitated foot processes with filtration slits in between …
[PDF][PDF] Autoantibodies targeting nephrin in podocytopathies
FE Hengel, S Dehde, M Lassé, G Zahner, L Seifert… - N Engl J Med, 2024 - sfndt.org
Le syndrome néphrotique à lésions glomérulaires minimes (LGM) et la hyalinose
segmentaire et focale (HSF) primitive sont deux pathologies glomérulaires qui entrainent un …
segmentaire et focale (HSF) primitive sont deux pathologies glomérulaires qui entrainent un …
A molecular mechanism explaining albuminuria in kidney disease
Mammalian kidneys constantly filter large amounts of liquid, with almost complete retention
of albumin and other macromolecules in the plasma. Breakdown of the three-layered renal …
of albumin and other macromolecules in the plasma. Breakdown of the three-layered renal …
Extracellular matrix molecules: potential targets in pharmacotherapy
H Järveläinen, A Sainio, M Koulu, TN Wight… - Pharmacological …, 2009 - Elsevier
The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
[HTML][HTML] The podocyte's response to injury: role in proteinuria and glomerulosclerosis
SJ Shankland - Kidney international, 2006 - Elsevier
The terminally differentiated podocyte, also called glomerular visceral epithelial cell, are
highly specialized cells. They function as a critical size and charge barrier to prevent …
highly specialized cells. They function as a critical size and charge barrier to prevent …
Acute kidney injury and progression of diabetic kidney disease
Diabetic kidney disease, commonly termed diabetic nephropathy (DN), is the most common
cause of end-stage kidney disease (ESKD) worldwide. The characteristic histopathology of …
cause of end-stage kidney disease (ESKD) worldwide. The characteristic histopathology of …
Podocyte biology and response to injury
P Mundel, SJ Shankland - Journal of the American Society of …, 2002 - journals.lww.com
The visceral glomerular epithelial cell, also called podocyte, is a terminally differentiated cell
that lines the outer aspect of the glomerular basement membrane (GBM). It therefore forms …
that lines the outer aspect of the glomerular basement membrane (GBM). It therefore forms …
The podocyte slit diaphragm—from a thin grey line to a complex signalling hub
The architectural design of our kidneys is amazingly complex, and culminates in the 3D
structure of the glomerular filter. During filtration, plasma passes through a sieve consisting …
structure of the glomerular filter. During filtration, plasma passes through a sieve consisting …
Hereditary proteinuria syndromes and mechanisms of proteinuria
K Tryggvason, J Patrakka… - New England Journal of …, 2006 - Mass Medical Soc
Hereditary Proteinuria Syndromes and Mechanisms of Proteinuria | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …