Functional nanomaterials for phototherapies of cancer

L Cheng, C Wang, L Feng, K Yang, Z Liu - Chemical reviews, 2014 - ACS Publications
Cancer has been one of the major threats to the lives of human beings for centuries.(1)
Current cancer therapies mainly include surgery, chemotherapies, and radiotherapies …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …

Metalloporphyrin-encapsulated biodegradable nanosystems for highly efficient magnetic resonance imaging-guided sonodynamic cancer therapy

P Huang, X Qian, Y Chen, L Yu, H Lin… - Journal of the …, 2017 - ACS Publications
Traditional photodynamic therapy (PDT) suffers from the critical issues of low tissue-
penetrating depth of light and potential phototoxicity, which are expected to be solved by …

Photodynamic therapy: past, present and future

U Chilakamarthi, L Giribabu - The Chemical Record, 2017 - Wiley Online Library
Though we crossed many milestones in the field of medicine and health care in eradicating
some deadly diseases over the past decades, cancer remained a challenge taking the lives …

Impacts of mesoporous silica nanoparticle size, pore ordering, and pore integrity on hemolytic activity

YS Lin, CL Haynes - Journal of the American Chemical Society, 2010 - ACS Publications
This paper uses the measure of hemolysis to evaluate the toxicity of nonporous and porous
silica nanoparticles with varied sizes and investigates the effects of porous structure and …

[HTML][HTML] Light-activated hypoxia-responsive nanocarriers for enhanced anticancer therapy

C Qian, J Yu, Y Chen, Q Hu, X **ao, W Sun… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed
for efficiently producing singlet oxygen (1O2) and inducing hypoxia to promote release of its …

Mesoporous silica nanoparticle based nano drug delivery systems: synthesis, controlled drug release and delivery, pharmacokinetics and biocompatibility

Q He, J Shi - Journal of Materials Chemistry, 2011 - pubs.rsc.org
The biomedical applications of mesoporous silica nanoparticles (MSNs) as efficient drug
delivery carriers have attracted great attention in the last decade. The structure, morphology …

Nonporous silica nanoparticles for nanomedicine application

L Tang, J Cheng - Nano today, 2013 - Elsevier
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to
change the landscape of the diagnosis and therapy of many diseases. In the past several …

Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery

J Zhang, ZF Yuan, Y Wang, WH Chen… - Journal of the …, 2013 - ACS Publications
A novel type of cellular-uptake-shielding multifunctional envelope-type mesoporous silica
nanoparticle (MEMSN) was designed for tumor-triggered targeting drug delivery to …