[HTML][HTML] Advances in growth factor delivery for bone tissue engineering

ÉR Oliveira, L Nie, D Podstawczyk… - International journal of …, 2021‏ - mdpi.com
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018‏ - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Growth factor delivery: Defining the next generation platforms for tissue engineering

LMC Aguilar, SM Silva, SE Moulton - Journal of controlled Release, 2019‏ - Elsevier
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

K Lee, EA Silva, DJ Mooney - Journal of the Royal …, 2011‏ - royalsocietypublishing.org
The identification and production of recombinant morphogens and growth factors that play
key roles in tissue regeneration have generated much enthusiasm and numerous clinical …

Resolution of inflammation in bone regeneration: From understandings to therapeutic applications

H Newman, YV Shih, S Varghese - Biomaterials, 2021‏ - Elsevier
Impaired bone healing occurs in 5–10% of cases following injury, leading to a significant
economic and clinical impact. While an inflammatory response upon injury is necessary to …

Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering

SH Lee, H Shin - Advanced drug delivery reviews, 2007‏ - Elsevier
Regeneration of bone and cartilage defects can be accelerated by localized delivery of
appropriate growth factors incorporated within biodegradable carriers. The carrier …

Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine

R Subbiah, RE Guldberg - Advanced healthcare materials, 2019‏ - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

The challenge of establishing preclinical models for segmental bone defect research

JC Reichert, S Saifzadeh, ME Wullschleger, DR Epari… - Biomaterials, 2009‏ - Elsevier
A considerable number of international research groups as well as commercial entities work
on the development of new bone grafting materials, carriers, growth factors and specifically …

Tissue engineering strategies for promoting vascularized bone regeneration

S Almubarak, H Nethercott, M Freeberg, C Beaudon… - Bone, 2016‏ - Elsevier
This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …

Silk implants for the healing of critical size bone defects

L Meinel, R Fajardo, S Hofmann, R Langer, J Chen… - Bone, 2005‏ - Elsevier
Bone (re)-generation and bone fixation strategies utilize biomaterial implants, which are
gradually replaced by autologous tissues. Ideally, these biomaterials should be …