▪ Abstract Large-genome eukaryotes use heritable cytosine methylation to silence
promoters, especially those associated with transposons and imprinted genes. Cytosine …

Transcription factor (TF) DNA sequence preferences direct their regulatory activity, but are
currently known for only∼ 1% of eukaryotic TFs. Broadly sampling DNA-binding domain …

The CCAAT box promoter element and NF-Y, the transcription factor (TF) that binds to it,
were among the first cis-elements and trans-acting factors identified; their interplay is …

How growth regulators provoke context-specific signals is a fundamental question in
developmental biology. In plants, both auxin and brassinosteroids (BRs) promote cell …

Genomes encode for genes and non-coding DNA, both capable of transcriptional activity.
However, unlike canonical genes, many transcripts from non-coding DNA have limited …

Background The regulatory mechanisms underlying tissue specificity are a crucial part of the
development and maintenance of multicellular organisms. A genome-wide analysis of …

Abstract The DIURNAL project (http://diurnal. cgrb. oregonstate. edu/) provides a graphical
interface for mining and viewing diurnal and circadian microarray data for Arabidopsis …

The identity and developmental potential of a human cell is specified by its epigenome that
is largely defined by patterns of chromatin modifications including histone acetylation. Here …

Ultraviolet (UV) light is a natural genotoxic agent leading to the formation of photolesions
endangering the genomic integrity and thereby the survival of living organisms. To prevent …

The Y box is an important sequence motif found in promoters and enhancers containing a
CCAAT box–one of the few elements enriched in promoters of large sets of genes …