Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
Arterial spin labeling perfusion of the brain: emerging clinical applications
Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …
Machine learning framework for early MRI-based Alzheimer's conversion prediction in MCI subjects
Mild cognitive impairment (MCI) is a transitional stage between age-related cognitive
decline and Alzheimer's disease (AD). For the effective treatment of AD, it would be …
decline and Alzheimer's disease (AD). For the effective treatment of AD, it would be …
The use of neuroimaging techniques in the early and differential diagnosis of dementia
Dementia is a leading cause of disability and death worldwide. At present there is no
disease modifying treatment for any of the most common types of dementia such as …
disease modifying treatment for any of the most common types of dementia such as …
A neuroradiologist's guide to arterial spin labeling MRI in clinical practice
M Grade, JA Hernandez Tamames, FB Pizzini… - Neuroradiology, 2015 - Springer
Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …
(CBF). This review provides a practical guide and overview of the clinical applications of …
Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?
K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …
research following several theoretical and clinical lines, all existing treatments for the …
Associations between vascular function and tau PET are associated with global cognition and amyloid
D Albrecht, AL Isenberg, J Stradford… - Journal of …, 2020 - Soc Neuroscience
Tau pathology and vascular dysfunction are important contributors to Alzheimer's disease
(AD), but vascular–tau associations and their effects on cognition are poorly understood. We …
(AD), but vascular–tau associations and their effects on cognition are poorly understood. We …
Prediction and classification of Alzheimer disease based on quantification of MRI deformation
X Long, L Chen, C Jiang, L Zhang… - PloS one, 2017 - journals.plos.org
Detecting early morphological changes in the brain and making early diagnosis are
important for Alzheimer's disease (AD). High resolution magnetic resonance imaging can be …
important for Alzheimer's disease (AD). High resolution magnetic resonance imaging can be …
[HTML][HTML] Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease
Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …
Ketogenic medium chain triglycerides increase brain energy metabolism in Alzheimer's disease
Background: In Alzheimer's disease (AD), it is unknown whether the brain can utilize
additional ketones as fuel when they are derived from a medium chain triglyceride (MCT) …
additional ketones as fuel when they are derived from a medium chain triglyceride (MCT) …